RESPONSE AND PHYSIOLOGIC OUTCOMES AFTER BUTORPHANOL, MIDAZOLAM, AND MEDETOMIDINE IMMOBILIZATION AND REVERSAL IN CAPTIVE REINDEER (RANGIFER TARANDUS).

IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES
Lauren Ienello, Anne Rivas, Laura Martinelli, Adrienne Haley, Jessica Byrne, Erin Wendt-Hornickle
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引用次数: 0

Abstract

Sedation, recovery response, and physiologic outcomes were evaluated in five captive reindeer (Rangifer tarandus) in Minnesota using a completely reversible immobilization protocol. Reindeer were immobilized with butorphanol (0.23-0.32 mg/kg), midazolam (0.23-0.32 mg/kg), and medetomidine (0.15 mg/kg) (BMM) via IM dart. Induction time (IT), recumbency time (DT), and recovery time (RT) were recorded. Temperature (T), respiratory rate (RR), pulse rate (PR), pulse oximetry (SpO2), arterial blood gas values including oxygen (PaO2), and carbon dioxide (PaCO2) tensions and lactate (Lac) were recorded preoxygen supplementation and 15 min postoxygen supplementation. Reversal was done using naltrexone (2.3-3.0 mg/kg), flumazenil (0.008-0.01 mg/kg) and atipamezole (0.62-0.78 mg/kg) (NFA) IM, limiting recumbency to 1 h. Median IT, DT, and RT were 5 min, 46 min, and 7 min, respectively. SpO2 (92 to 99%, P = 0.125), PaO2 (45.5 to 97 mmHg, P = 0.25), and PaCO2 (46.5 to 54.6 mmHg, P = 0.25) all increased, whereas Lac (3.02 to 1.93 mmol/L, P = 0.25) decreased between baseline and 15 min postoxygen supplementation, without statistical significance. BMM immobilization, and reversal with NFA provided rapid and effective immobilization and recovery, respectively. Oxygen supplementation mitigated hypoxemia in all reindeer.

圈养驯鹿(rangifer tarandus)在接受丁吗啡诺、咪达唑仑和美托咪定固定和逆转后的反应和生理结果。
采用完全可逆的固定方案对明尼苏达州的五头圈养驯鹿(Rangifer tarandus)进行了镇静、恢复反应和生理结果评估。驯鹿使用丁吗啡诺(0.23-0.32 毫克/千克)、咪达唑仑(0.23-0.32 毫克/千克)和美托咪定(0.15 毫克/千克)(BMM)通过 IM 注射器固定。记录诱导时间(IT)、静卧时间(DT)和恢复时间(RT)。记录补氧前和补氧后 15 分钟的体温(T)、呼吸频率(RR)、脉搏频率(PR)、脉搏血氧饱和度(SpO2)、动脉血气值,包括氧气(PaO2)、二氧化碳(PaCO2)张力和乳酸(Lac)。使用纳曲酮(2.3-3.0 毫克/千克)、氟马西尼(0.008-0.01 毫克/千克)和阿替帕唑(0.62-0.78 毫克/千克)(NFA)IM 进行逆转,限制患者在 1 小时内的休眠。从基线到补氧后 15 分钟,SpO2(92% 到 99%,P = 0.125)、PaO2(45.5 到 97 mmHg,P = 0.25)和 PaCO2(46.5 到 54.6 mmHg,P = 0.25)均有所上升,而 Lac(3.02 到 1.93 mmol/L,P = 0.25)有所下降,但无统计学意义。BMM 固定和使用 NFA 逆转分别提供了快速有效的固定和恢复。补氧缓解了所有驯鹿的低氧血症。
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来源期刊
Journal of Zoo and Wildlife Medicine
Journal of Zoo and Wildlife Medicine 农林科学-兽医学
CiteScore
1.70
自引率
14.30%
发文量
74
审稿时长
9-24 weeks
期刊介绍: The Journal of Zoo and Wildlife Medicine (JZWM) is considered one of the major sources of information on the biology and veterinary aspects in the field. It stems from the founding premise of AAZV to share zoo animal medicine experiences. The Journal evolved from the long history of members producing case reports and the increased publication of free-ranging wildlife papers. The Journal accepts manuscripts of original research findings, case reports in the field of veterinary medicine dealing with captive and free-ranging wild animals, brief communications regarding clinical or research observations that may warrant publication. It also publishes and encourages submission of relevant editorials, reviews, special reports, clinical challenges, abstracts of selected articles and book reviews. The Journal is published quarterly, is peer reviewed, is indexed by the major abstracting services, and is international in scope and distribution. Areas of interest include clinical medicine, surgery, anatomy, radiology, physiology, reproduction, nutrition, parasitology, microbiology, immunology, pathology (including infectious diseases and clinical pathology), toxicology, pharmacology, and epidemiology.
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