CLINICAL AND PATHOLOGIC FINDINGS IN IGUANIDS WITH SODIUM URATE CHOLELITHIASIS.

IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES
Paula Rodriguez, Danielle K Tarbert, Frank Ridgley, Kenneth J Conley, James Steeil, Rachel E Burns, Meg Sutherland-Smith, Karen Rosenthal, Joanne R Paul-Murphy
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引用次数: 0

Abstract

Four green iguanas (Iguana iguana) and one blue iguana (Cyclura lewisi) from five facilities were diagnosed with sodium urate cholelithiasis. One case was diagnosed antemortem via ultrasonography, and the iguana underwent a choledochotomy for treatment. The other four cases were identified at necropsy. Pathologic hepatic and biliary changes were present in four of the five cases at necropsy. Histologically, four iguanas had hepatic fibrosis, three had bile duct hyperplasia, and one had cholangiohepatitis and pancreaticocholedochitis. Two iguanas had pathologic renal changes. This is the first report of sodium urate cholelithiasis in reptiles. This case series highlights the potential significant clinical disease caused by sodium urate cholelithiasis and the importance of biliary system evaluation. Further investigation is recommended to explore the pathogenesis of reptilian sodium urate cholelith formation.

尿酸钠胆石症鬣蜥的临床和病理发现。
来自五个设施的四只绿鬣蜥(Iguana iguana)和一只蓝鬣蜥(Cyclura lewisi)被诊断出患有尿酸钠性胆石症。其中一例是在死前通过超声波检查确诊的,鬣蜥接受了胆总管切开术治疗。另外四例是在尸体解剖时发现的。尸体解剖时,五例病例中有四例出现肝胆病变。从组织学角度看,四只鬣蜥有肝纤维化,三只有胆管增生,一只有胆管炎和胰胆管炎。两只鬣蜥的肾脏出现病理变化。这是首次报道爬行动物尿酸钠胆石症。该系列病例强调了尿酸钠胆石症可能引起的重大临床疾病以及胆道系统评估的重要性。建议进一步研究爬行动物尿酸钠胆石形成的发病机制。
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来源期刊
Journal of Zoo and Wildlife Medicine
Journal of Zoo and Wildlife Medicine 农林科学-兽医学
CiteScore
1.70
自引率
14.30%
发文量
74
审稿时长
9-24 weeks
期刊介绍: The Journal of Zoo and Wildlife Medicine (JZWM) is considered one of the major sources of information on the biology and veterinary aspects in the field. It stems from the founding premise of AAZV to share zoo animal medicine experiences. The Journal evolved from the long history of members producing case reports and the increased publication of free-ranging wildlife papers. The Journal accepts manuscripts of original research findings, case reports in the field of veterinary medicine dealing with captive and free-ranging wild animals, brief communications regarding clinical or research observations that may warrant publication. It also publishes and encourages submission of relevant editorials, reviews, special reports, clinical challenges, abstracts of selected articles and book reviews. The Journal is published quarterly, is peer reviewed, is indexed by the major abstracting services, and is international in scope and distribution. Areas of interest include clinical medicine, surgery, anatomy, radiology, physiology, reproduction, nutrition, parasitology, microbiology, immunology, pathology (including infectious diseases and clinical pathology), toxicology, pharmacology, and epidemiology.
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