Sex Differences in Effects of Exercise on Physical Function in Aging: A Systematic Review with Meta-Analysis.

IF 4 3区医学 Q1 ANDROLOGY

World Journal of Mens Health Pub Date : 2024-10-01 Epub Date: 2024-02-07 DOI:10.5534/wjmh.230257

Rubén Fernández-Rodríguez, Vicente Martínez-Vizcaíno, Sara Reina-Gutiérrez, Bruno Bizzozero-Peroni, Ana Torres-Costoso, Eva Rodríguez-Gutiérrez, Valentina Díaz-Goñi, Cristina Cadenas-Sánchez

{"title":"Sex Differences in Effects of Exercise on Physical Function in Aging: A Systematic Review with Meta-Analysis.","authors":"Rubén Fernández-Rodríguez, Vicente Martínez-Vizcaíno, Sara Reina-Gutiérrez, Bruno Bizzozero-Peroni, Ana Torres-Costoso, Eva Rodríguez-Gutiérrez, Valentina Díaz-Goñi, Cristina Cadenas-Sánchez","doi":"10.5534/wjmh.230257","DOIUrl":null,"url":null,"abstract":"Purpose: Our objective was to synthesize and determine whether there are sex differences in physical function following exercise interventions in older adults.Materials and methods: A systematic search was conducted in four databases from inception to July 8th, 2023 searching for prospective trials that conducted exercise interventions in older adults and results for physical function were reported by sex. Pooled standardized mean differences (SMDs) with their 95% confidence intervals (CIs) were estimated using a randomeffects method. The Sidik-Jonkman estimator was used to calculate the variance of heterogeneity (I²).Results: A total of 19 studies involving 20,133 older adults (mean age ≥60 years, 33.7% female) were included. After exercise interventions, males reported significantly greater pre-post changes compared to females for upper body strength (SMD=-0.40, 95% CI: -0.71 to -0.09; I²=75.6%; n=8), lower body strength (SMD=-0.32, 95% CI: -0.55 to -0.10; I²=52.0%; n=11), and cardiorespiratory fitness (SMD=-0.29, 95% CI: -0.48 to -0.10; I²=89.1%; n=12). Conversely, the pooled SMDs showed a significant effect favoring females for motor fitness (SMD=0.21, 95% CI: 0.03 to 0.39; I²=0%; n=7). Limited and inconsistent results were observed for flexibility.Conclusions: Our study suggests the existence of sex-related differences on physical function after an exercise intervention in the older population.","PeriodicalId":54261,"journal":{"name":"World Journal of Mens Health","volume":" ","pages":"694-711"},"PeriodicalIF":4.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439799/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Mens Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5534/wjmh.230257","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/7 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"ANDROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: Our objective was to synthesize and determine whether there are sex differences in physical function following exercise interventions in older adults.

Materials and methods: A systematic search was conducted in four databases from inception to July 8th, 2023 searching for prospective trials that conducted exercise interventions in older adults and results for physical function were reported by sex. Pooled standardized mean differences (SMDs) with their 95% confidence intervals (CIs) were estimated using a randomeffects method. The Sidik-Jonkman estimator was used to calculate the variance of heterogeneity (I²).

Results: A total of 19 studies involving 20,133 older adults (mean age ≥60 years, 33.7% female) were included. After exercise interventions, males reported significantly greater pre-post changes compared to females for upper body strength (SMD=-0.40, 95% CI: -0.71 to -0.09; I²=75.6%; n=8), lower body strength (SMD=-0.32, 95% CI: -0.55 to -0.10; I²=52.0%; n=11), and cardiorespiratory fitness (SMD=-0.29, 95% CI: -0.48 to -0.10; I²=89.1%; n=12). Conversely, the pooled SMDs showed a significant effect favoring females for motor fitness (SMD=0.21, 95% CI: 0.03 to 0.39; I²=0%; n=7). Limited and inconsistent results were observed for flexibility.

Conclusions: Our study suggests the existence of sex-related differences on physical function after an exercise intervention in the older population.

查看原文本刊更多论文

运动对老年身体功能影响的性别差异：带 Meta 分析的系统性综述》。

目的：我们的目的是综合分析并确定老年人运动干预后身体功能是否存在性别差异：从开始到2023年7月8日，我们在四个数据库中进行了系统性检索，搜索对老年人进行运动干预的前瞻性试验，并按性别报告了身体功能的结果。采用随机效应法估算了汇总的标准化均值差异（SMDs）及其95%置信区间（CIs）。使用 Sidik-Jonkman 估计器计算异质性方差（I²）：共纳入了 19 项研究，涉及 20133 名老年人（平均年龄≥60 岁，33.7% 为女性）。运动干预后，男性上肢力量（SMD=-0.40，95% CI：-0.71 至 -0.09；I²=75.6%；n=8）、下肢力量（SMD=-0.32，95% CI：-0.55 至 -0.10；I²=52.0%；n=11）和心肺功能（SMD=-0.29，95% CI：-0.48 至 -0.10；I²=89.1%；n=12）的事后变化明显大于女性。相反，汇总的 SMD 显示，女性在运动健身方面具有显著的优势（SMD=0.21，95% CI：0.03 至 0.39；I²=0%；n=7）。在柔韧性方面观察到的结果有限且不一致：我们的研究表明，在老年人群中，运动干预后身体功能的性别差异是存在的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

World Journal of Mens Health Medicine-Psychiatry and Mental Health

CiteScore

7.60

自引率

2.10%

发文量

审稿时长

6 weeks