Athanasios Rempakos, Michaella Alexandrou, Deniz Mutlu, James W Choi, Paul Poommipanit, Jaikirshan J Khatri, Laura Young, Philip Dattilo, Yasser Sadek, Rhian Davies, Sevket Gorgulu, Farouc A Jaffer, Raj Chandwaney, Brian Jefferson, Baseem Elbarouni, Lorenzo Azzalini, Kathleen E Kearney, Khaldoon Alaswad, Mir B Basir, Oleg Krestyaninov, Dmitrii Khelimskii, Nazif Aygul, Nidal Abi-Rafeh, Ahmed Elguindy, Omer Goktekin, Bavana V Rangan, Olga C Mastrodemos, Ahmed Al-Ogaili, Yader Sandoval, M Nicholas Burke, Emmanouil S Brilakis, Arun Kalyanasundaram
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引用次数: 0
Abstract
Background: Antegrade wiring is the most commonly used chronic total occlusion (CTO) crossing technique.
Methods: Using data from the PROGRESS CTO registry (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention; Clinicaltrials.gov identifier: NCT02061436), we examined the clinical and angiographic characteristics and procedural outcomes of CTO percutaneous coronary interventions (PCIs) performed using a primary antegrade wiring strategy.
Results: Of the 13 563 CTO PCIs performed at 46 centers between 2012 and 2023, a primary antegrade wiring strategy was used in 11 332 (83.6%). Upon multivariable logistic regression analysis, proximal cap ambiguity (odds ratio [OR]: 0.52; 95% CI, 0.46-0.59), side branch at the proximal cap (OR: 0.85; 95% CI, 0.77-0.95), blunt/no stump (OR: 0.52; 95% CI: 0.47-0.59), increasing lesion length (OR [per 10 mm increase]: 0.79; 95% CI, 0.76-0.81), moderate to severe calcification (OR: 0.73; 95% CI, 0.66-0.81), moderate to severe proximal tortuosity (OR: 0.67; 95% CI, 0.59-0.75), bifurcation at the distal cap (OR: 0.66; 95% CI, 0.59-0.73), left anterior descending artery CTO (OR [vs right coronary artery]: 1.44; 95% CI, 1.28-1.62) and left circumflex CTO (OR [vs right coronary artery]: 1.22; 95% CI, 1.07-1.40), non-in-stent restenosis lesion (OR: 0.56; 95% CI, 0.49-0.65), and good distal landing zone (OR: 1.18; 95% CI, 1.06-1.32) were independently associated with primary antegrade wiring crossing success.
Conclusions: The use of antegrade wiring as the initial strategy was high (83.6%) in our registry. We identified several parameters associated with primary antegrade wiring success.
期刊介绍:
The Journal of Invasive Cardiology will consider for publication suitable articles on topics pertaining to the invasive treatment of patients with cardiovascular disease.