Critical illness-associated limb and diaphragmatic weakness.

IF 3.5 3区 医学 Q1 CRITICAL CARE MEDICINE
Current Opinion in Critical Care Pub Date : 2024-04-01 Epub Date: 2024-01-16 DOI:10.1097/MCC.0000000000001135
Valentine Le Stang, Nicola Latronico, Martin Dres, Michele Bertoni
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引用次数: 0

Abstract

Purpose of review: In the current review, we aim to highlight the evolving evidence on the diagnosis, prevention and treatment of critical illness weakness (CIW) and critical illness associated diaphragmatic weakness (CIDW).

Recent findings: In the ICU, several risk factors can lead to CIW and CIDW. Recent evidence suggests that they have different pathophysiological mechanisms and impact on outcomes, although they share common risk factors and may overlap in several patients. Their diagnosis is challenging, because CIW diagnosis is primarily clinical and, therefore, difficult to obtain in the ICU population, and CIDW diagnosis is complex and not easily performed at the bedside. All of these issues lead to underdiagnosis of CIW and CIDW, which significantly increases the risk of complications and the impact on both short and long term outcomes. Moreover, recent studies have explored promising diagnostic techniques that are may be easily implemented in daily clinical practice. In addition, this review summarizes the latest research aimed at improving how to prevent and treat CIW and CIDW.

Summary: This review aims to clarify some uncertain aspects and provide helpful information on developing monitoring techniques and therapeutic interventions for managing CIW and CIDW.

与危重病有关的肢体和膈肌无力。
综述的目的:在本综述中,我们旨在强调危重病乏力(CIW)和危重病相关膈肌无力(CIDW)的诊断、预防和治疗方面不断发展的证据:在重症监护室中,多种风险因素可导致危重病乏力和危重病相关膈肌无力。最近的证据表明,这两种疾病具有不同的病理生理机制和对预后的影响,尽管它们有共同的风险因素,并可能在一些患者身上发生重叠。它们的诊断具有挑战性,因为 CIW 诊断主要是临床诊断,因此很难在重症监护室人群中获得,而 CIDW 诊断则很复杂,不易在床边进行。所有这些问题都会导致 CIW 和 CIDW 诊断不足,从而大大增加并发症的风险以及对短期和长期预后的影响。此外,近期的研究探索了一些很有前景的诊断技术,这些技术在日常临床实践中很容易应用。此外,本综述还总结了旨在改善 CIW 和 CIDW 预防和治疗方法的最新研究。摘要:本综述旨在澄清一些不确定的方面,并为开发用于管理 CIW 和 CIDW 的监测技术和治疗干预措施提供有用信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Opinion in Critical Care
Current Opinion in Critical Care 医学-危重病医学
CiteScore
5.90
自引率
3.00%
发文量
172
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​​​Current Opinion in Critical Care delivers a broad-based perspective on the most recent and most exciting developments in critical care from across the world. Published bimonthly and featuring thirteen key topics – including the respiratory system, neuroscience, trauma and infectious diseases – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.
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