Innovating dialysis through computational modelling of hollow-fibre haemodialysers

IF 28.6 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Nephrology Pub Date : 2024-03-04 DOI:10.1038/s41581-024-00826-0

Ruhit Sinha, Michael V. Rocco, Pirouz Daeihagh, Anne E. Staples

引用次数: 0

Abstract

Haemodialyser technology has not advanced much in decades, despite its unresolved shortcomings. Sophisticated new computational tools such as high-fidelity surrogate in silico dialyser models could reduce the time and expense of exploring alternative designs, dialysis dose and operating conditions compared with the current gold standard in vitro studies.

查看原文本刊更多论文

通过中空纤维血液透析器的计算建模创新透析技术

尽管血液透析器技术的缺陷尚未得到解决，但几十年来该技术并没有取得多大进展。与目前的黄金标准体外研究相比，新的先进计算工具（如高保真代理硅学透析器模型）可以减少探索替代设计、透析剂量和操作条件所需的时间和费用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nature Reviews Nephrology 医学-泌尿学与肾脏学

CiteScore

39.00

自引率

1.20%

发文量

127

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Nephrology aims to be the premier source of reviews and commentaries for the scientific communities it serves. It strives to publish authoritative, accessible articles. Articles are enhanced with clearly understandable figures, tables, and other display items. Nature Reviews Nephrology publishes Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements. The content is relevant to nephrologists and basic science researchers. The broad scope of the journal ensures that the work reaches the widest possible audience.