The weight of complications: high and low BMI have disparate modes of failure in total hip arthroplasty.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Jessica Schmerler, Victoria E Bergstein, William ElNemer, Andrew B Harris, Harpal S Khanuja, Uma Srikumaran, Vishal Hegde
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Abstract

Background: Body mass index (BMI) has been shown to influence risk for revision total hip arthroplasty (rTHA), but few studies have specifically examined which causes of rTHA are most likely in different BMI classes. We hypothesized that patients in different BMI classes would undergo rTHA for disparate reasons.

Methods: Ninety-eight thousand six hundred seventy patients undergoing rTHA over 2006-2020 were identified in the National Inpatient Sample. Patients were classified as underweight, normal-weight, overweight/obese, or morbidly obese. Multivariable logistic regression was used to analyze the impact of BMI on rTHA for periprosthetic joint infection (PJI), dislocation, periprosthetic fracture (PPF), aseptic loosening, or mechanical complications. Analyses were adjusted for age, sex, race/ethnicity, socioeconomic status, insurance, geographic region, and comorbidities.

Results: Compared to normal-weight patients, underweight patients were 131% more likely to have a revision due to dislocation and 63% more likely due to PPF. Overweight/obese patients were 19% less likely to have a revision due to dislocation and 10% more likely due to PJI. Cause for revision in morbidly obese patients was 4s1% less likely to be due to dislocation, 8% less likely due to mechanical complications, and 90% more likely due to PJI.

Conclusions: Overweight/obese and morbidly obese patients were more likely to undergo rTHA for PJI and less likely for mechanical reasons compared to normal weight patients. Underweight patients were more likely to undergo rTHA for dislocation or PPF. Understanding the differences in cause for rTHA among the BMI classes can aid in patient-specific optimization and management to reduce postoperative complications.

Level of evidence: III.

并发症的重量:高和低体重指数在全髋关节置换术中的失败模式不同。
背景:身体质量指数(BMI)已被证明会影响翻修全髋关节置换术(rTHA)的风险,但很少有研究专门研究不同BMI等级的患者最有可能接受rTHA的原因。我们假设不同体重指数级别的患者接受 rTHA 的原因各不相同:在全国住院病人样本中确定了 2006-2020 年间接受 rTHA 的 98,670 名病人。患者被分为体重不足、正常体重、超重/肥胖或病态肥胖。采用多变量逻辑回归分析 BMI 对假体周围关节感染 (PJI)、脱位、假体周围骨折 (PPF)、无菌性松动或机械并发症的影响。分析对年龄、性别、种族/民族、社会经济状况、保险、地理区域和合并症进行了调整:与体重正常的患者相比,体重不足的患者因脱位而进行翻修的可能性增加了131%,因PPF而进行翻修的可能性增加了63%。超重/肥胖患者因脱位而翻修的可能性降低19%,因PJI而翻修的可能性增加10%。病态肥胖患者因脱位而翻修的可能性降低了4%,因机械并发症而翻修的可能性降低了8%,因PJI而翻修的可能性增加了90%:结论:与体重正常的患者相比,超重/肥胖和病态肥胖患者更有可能因PJI而接受rTHA,而因机械性原因接受rTHA的可能性较低。体重不足的患者更有可能因脱位或PPF而接受rTHA。了解不同体重指数等级的患者接受 rTHA 的原因差异有助于针对患者进行优化和管理,以减少术后并发症:证据等级:III。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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