Influence of keratinized mucosa width on the resolution of peri-implant mucositis: A prospective cohort study

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research Pub Date : 2024-03-01 DOI:10.1111/cid.13317

Gonzalo Blasi, Francesco Chierico, Ettore Amerio, Gerard Àlvarez, Sergio Isabal, Alexandre Arredondo, Vanessa Blanc, José Nart, Alberto Monje

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引用次数: 0

Abstract

Background

The prevalence of peri-implant diseases, driven by biofilm accumulation and influenced by factors such as the width of keratinized mucosa (KM), underscores the need for understanding their etiology and management.

Purpose

To evaluate the association between the KM width and the clinical resolution of peri-implant mucositis after mechanical therapy.

Materials and methods

Patients with an implant diagnosed with peri-implant mucositis were allocated to two groups: wide band of KM (WKM ≥ 2 mm) and narrow/no band of KM (NKM < 2 mm). Data and submucosa biofilm were collected at baseline and at 8, 12, and 24 weeks after nonsurgical therapy. A Brunner–Langer model was estimated for longitudinal data to evaluate and compare changes in any clinical parameter throughout follow-up between both groups. Furthermore, the microbial profiles were evaluated by 16S rRNA gene sequencing.

Results

A total of 38 implants were analyzed. At 24 weeks, bleeding on probing was substantially reduced in both groups, reaching statistical significance (p < 0.001). Treatment resulted in 23.9% less effective in achieving success for NKM. As such, NKM reduced the odds of disease resolution by 80% compared to WKM. The rest of the explored clinical parameters yielded more favorable outcomes for WKM versus NKM. Neither the alpha nor the beta diversity of the microbial profiles were significantly modulated by KM.

Conclusions

KM width influences the clinical resolution of peri-implant mucositis after mechanical therapy (https://clinicaltrials.gov/study/NCT04874467?cond=keratinized%20mucosa&rank=8, NCT04874467, 04/30/2021).

查看原文本刊更多论文

角化粘膜宽度对种植体周围粘膜炎缓解的影响：前瞻性队列研究。

背景：目的：评估KM宽度与机械治疗后种植体周围粘膜炎临床缓解之间的关系：将被诊断为种植体周围粘膜炎的种植体患者分为两组：宽KM带（WKM ≥ 2 mm）和窄/无KM带（NKM 结果：共分析了 38 个种植体。24 周时，两组的探诊出血量均大幅减少，达到统计学意义（p 结论：宽带 KM 和窄带 KM 对临床上牙周出血的解决有影响：KM宽度影响机械治疗后种植体周围粘膜炎的临床缓解（https://clinicaltrials.gov/study/NCT04874467?cond=keratinized%20mucosa&rank=8，NCT04874467，04/30/2021）。

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来源期刊

Clinical Implant Dentistry and Related Research 医学-牙科与口腔外科

CiteScore

6.00

自引率

13.90%

发文量

103

审稿时长

4-8 weeks

期刊介绍： The goal of Clinical Implant Dentistry and Related Research is to advance the scientific and technical aspects relating to dental implants and related scientific subjects. Dissemination of new and evolving information related to dental implants and the related science is the primary goal of our journal. The range of topics covered by the journals will include but be not limited to: New scientific developments relating to bone Implant surfaces and their relationship to the surrounding tissues Computer aided implant designs Computer aided prosthetic designs Immediate implant loading Immediate implant placement Materials relating to bone induction and conduction New surgical methods relating to implant placement New materials and methods relating to implant restorations Methods for determining implant stability A primary focus of the journal is publication of evidenced based articles evaluating to new dental implants, techniques and multicenter studies evaluating these treatments. In addition basic science research relating to wound healing and osseointegration will be an important focus for the journal.