Bringing innovative wound care polymer materials to the market: Challenges, developments, and new trends

IF 15.2 1区 医学 Q1 PHARMACOLOGY & PHARMACY
Pegah Sanjarnia , Matías L. Picchio , Agustin N. Polegre Solis , Katharina Schuhladen , Patricia M. Fliss , Nikolaos Politakos , Lutz Metterhausen , Marcelo Calderón , Ernesto R. Osorio-Blanco
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引用次数: 0

Abstract

The development of innovative products for treating acute and chronic wounds has become a significant topic in healthcare, resulting in numerous products and innovations over time. The growing number of patients with comorbidities and chronic diseases, which may significantly alter, delay, or inhibit normal wound healing, has introduced considerable new challenges into the wound management scenario. Researchers in academia have quickly identified promising solutions, and many advanced wound healing materials have recently been designed; however, their successful translation to the market remains highly complex and unlikely without the contribution of industry experts. This review article condenses the main aspects of wound healing applications that will serve as a practical guide for researchers working in academia and industry devoted to designing, evaluating, validating, and translating polymer wound care materials to the market. The article highlights the current challenges in wound management, describes the state-of-the-art products already on the market and trending polymer materials, describes the regulation pathways for approval, discusses current wound healing models, and offers a perspective on new technologies that could soon reach consumers. We envision that this comprehensive review will significantly contribute to highlighting the importance of networking and exchanges between academia and healthcare companies. Only through the joint of these two actors, where innovation, manufacturing, regulatory insights, and financial resources act in harmony, can wound care products be developed efficiently to reach patients quickly and affordably.

Abstract Image

将创新的伤口护理聚合物材料推向市场:挑战、发展和新趋势。
开发治疗急性和慢性伤口的创新产品已成为医疗保健领域的一个重要课题,随着时间的推移,产品和创新层出不穷。越来越多的患者患有合并症和慢性疾病,这些疾病可能会严重改变、延迟或抑制正常的伤口愈合,这给伤口管理带来了相当大的新挑战。学术界的研究人员很快就找到了有前途的解决方案,最近还设计出了许多先进的伤口愈合材料;然而,如果没有行业专家的贡献,这些材料要成功推向市场仍然非常复杂,而且不太可能。这篇综述文章浓缩了伤口愈合应用的主要方面,将为致力于设计、评估、验证聚合物伤口护理材料并将其推向市场的学术界和工业界研究人员提供实用指南。文章强调了当前伤口管理面临的挑战,介绍了已上市的最先进产品和趋势性聚合物材料,描述了审批的监管途径,讨论了当前的伤口愈合模型,并对即将进入消费者视野的新技术进行了展望。我们认为,这篇综合评论将大大有助于强调学术界和医疗保健公司之间建立联系和交流的重要性。只有通过这两方面的联合,使创新、生产、监管见解和财政资源和谐共处,才能高效地开发出伤口护理产品,使其快速、经济地惠及患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
28.10
自引率
5.00%
发文量
294
审稿时长
15.1 weeks
期刊介绍: The aim of the Journal is to provide a forum for the critical analysis of advanced drug and gene delivery systems and their applications in human and veterinary medicine. The Journal has a broad scope, covering the key issues for effective drug and gene delivery, from administration to site-specific delivery. In general, the Journal publishes review articles in a Theme Issue format. Each Theme Issue provides a comprehensive and critical examination of current and emerging research on the design and development of advanced drug and gene delivery systems and their application to experimental and clinical therapeutics. The goal is to illustrate the pivotal role of a multidisciplinary approach to modern drug delivery, encompassing the application of sound biological and physicochemical principles to the engineering of drug delivery systems to meet the therapeutic need at hand. Importantly the Editorial Team of ADDR asks that the authors effectively window the extensive volume of literature, pick the important contributions and explain their importance, produce a forward looking identification of the challenges facing the field and produce a Conclusions section with expert recommendations to address the issues.
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