Delayed impacts of COVID-19 infection on unexplained male infertility: 2-year follow-up of normal sperm parameters in unexplained male infertility in KSA.

IF 0.7 Q4 UROLOGY & NEPHROLOGY
Urology Annals Pub Date : 2024-01-01 Epub Date: 2024-01-25 DOI:10.4103/ua.ua_154_22
Alsayed Saad Abdelaziz, Ayman Mohammed Ghoneem
{"title":"Delayed impacts of COVID-19 infection on unexplained male infertility: 2-year follow-up of normal sperm parameters in unexplained male infertility in KSA.","authors":"Alsayed Saad Abdelaziz, Ayman Mohammed Ghoneem","doi":"10.4103/ua.ua_154_22","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The current study aimed to assess the long-term effect of COVID-19 infection on unexplained male infertility.</p><p><strong>Materials and methods: </strong>A retrospective comparative study of 134 men attending the infertility outpatient clinic of our institution before exposing to COVID-19 infection in KSA from January 2019 to July 2022. Medical recorded data of these patients who were investigated before COVID-19 infection were retrospectively collected using the hospital's electronic database, including semen analysis, sex hormonal, and ultrasound testicular size, and their data were compared prospectively to collected data after 2-year follow-up.</p><p><strong>Results: </strong>One hundred and thirty-four infertile males who got COVID-19 infection in KSA (median age, 33 years) were assisted retrospectively preinfection and delayed 2 years postinfection (median of 23 months). Of the 134 men, 44 (32.83%) were asymptomatic positive COVID-19 (Group A), 68 (50.74%) had mild-to-moderate symptomatic positive COVID-19 (Group B), and 22 (16.41%) had severe symptomatic positive COVID-19 (Group C). There was no significant change between pre- and postinfections in sperm parameters, sex hormonal level, and testicular size. Subgroup analyses were performed for patients regarding the severity of infections. None of the evaluated parameters differed significantly after infections up to 2 years. Results of this study demonstrate that COVID-19 infection does not have significant changes in sperm parameters, sex hormonal level, and testicular size.</p><p><strong>Conclusion: </strong>The long-term impact of COVID-19 infections has no significant effect on normal sperm parameters, sex hormones, and testicular size in male infertility in KSA.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10896322/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Annals","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ua.ua_154_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/25 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: The current study aimed to assess the long-term effect of COVID-19 infection on unexplained male infertility.

Materials and methods: A retrospective comparative study of 134 men attending the infertility outpatient clinic of our institution before exposing to COVID-19 infection in KSA from January 2019 to July 2022. Medical recorded data of these patients who were investigated before COVID-19 infection were retrospectively collected using the hospital's electronic database, including semen analysis, sex hormonal, and ultrasound testicular size, and their data were compared prospectively to collected data after 2-year follow-up.

Results: One hundred and thirty-four infertile males who got COVID-19 infection in KSA (median age, 33 years) were assisted retrospectively preinfection and delayed 2 years postinfection (median of 23 months). Of the 134 men, 44 (32.83%) were asymptomatic positive COVID-19 (Group A), 68 (50.74%) had mild-to-moderate symptomatic positive COVID-19 (Group B), and 22 (16.41%) had severe symptomatic positive COVID-19 (Group C). There was no significant change between pre- and postinfections in sperm parameters, sex hormonal level, and testicular size. Subgroup analyses were performed for patients regarding the severity of infections. None of the evaluated parameters differed significantly after infections up to 2 years. Results of this study demonstrate that COVID-19 infection does not have significant changes in sperm parameters, sex hormonal level, and testicular size.

Conclusion: The long-term impact of COVID-19 infections has no significant effect on normal sperm parameters, sex hormones, and testicular size in male infertility in KSA.

COVID-19 感染对不明原因男性不育症的延迟影响:对阿联酋不明原因男性不育症患者正常精子参数的两年随访。
目的:本研究旨在评估 COVID-19 感染对不明原因男性不育的长期影响:对2019年1月至2022年7月期间在KSA感染COVID-19之前在本机构不孕不育门诊就诊的134名男性进行回顾性比较研究。利用医院电子数据库回顾性收集了这些在感染COVID-19前接受检查的患者的医疗记录数据,包括精液分析、性激素、超声睾丸大小等,并将其数据与2年随访后收集的数据进行前瞻性比较:对 134 名在 KSA 感染 COVID-19(中位年龄 33 岁)的不育男性进行了感染前和感染后 2 年(中位 23 个月)的回顾性辅助检查。在 134 名男性中,44 人(32.83%)为 COVID-19 无症状阳性(A 组),68 人(50.74%)为 COVID-19 轻度至中度症状阳性(B 组),22 人(16.41%)为 COVID-19 严重症状阳性(C 组)。感染前后,精子参数、性激素水平和睾丸大小均无明显变化。对感染严重程度不同的患者进行了分组分析。感染长达两年后,所有评估参数均无明显差异。本研究结果表明,COVID-19感染不会对精子参数、性激素水平和睾丸大小产生显著变化:COVID-19的长期感染对沙特男性不育症患者的正常精子参数、性激素水平和睾丸大小没有明显影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Urology Annals
Urology Annals UROLOGY & NEPHROLOGY-
CiteScore
1.20
自引率
0.00%
发文量
59
审稿时长
31 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信