Comparison of sperm retrieval rate between superficial and deep dissection during microscopic testicular sperm extraction.

IF 0.7 Q4 UROLOGY & NEPHROLOGY
Urology Annals Pub Date : 2024-01-01 Epub Date: 2024-01-25 DOI:10.4103/ua.ua_22_23
Hammam Mandourah, Mohammad Alghafees, Hamed Alali, Shaheed Alsuhaibani, Eyad Gutub, Lama Aldosari, Turki Alhumaid, Said Kattan, Naif Alhathal
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引用次数: 0

Abstract

Objective: The purpose of the study was to compare the outcome of microscopic testicular sperm extraction (micro-TESE) between superficial and deep dissection on the same testicle in terms of sperm retrieval rate (SRR).

Patients and methods: In a retrospective study from June 2019 to October 2021, 44 patients with nonobstructive azoospermia who underwent micro-TESE with positive results (mature sperm identified) were included. Eight patients were excluded from the study due to deficient documentation on superficial and deep dissection. A total of 36 patients were included; 60 testicles were examined for superficial and deep biopsies. Testicular histopathology was performed in all patients, and a hormonal evaluation was obtained before the micro-TESE attempt.

Results: Thirty-six patients and 60 testicles were included in the study. Of them, 47 (78.3%) testicles had positive results. Superficial TESE was positive in 38 (63.3%) testicles, and deep TESE was successful in 45 (75.0%) testicles. An improvement of 13.9% in the SRR was observed, following deep dissection. However, there was no statistically significant difference (P = 0.166). Rates of positive sperm retrieval (from any side) did not differ significantly based on patients' age, microdissection testicular sperm extraction sides, and hormonal concentrations; these differences were not apparent after superficial or deep TESE.

Conclusion: The presented findings suggest that although successful SRRs of deep TESE were higher than that of its superficial counterpart, there was no significant statistical difference. A larger body of evidence is needed to provide a higher grade of recommendation.

显微镜下睾丸取精术中浅层和深层剥离取精率的比较。
研究目的该研究旨在比较显微镜下睾丸取精术(micro-TESE)在同一睾丸上浅层和深层剥离的取精率(SRR)结果:在2019年6月至2021年10月的一项回顾性研究中,纳入了44名接受显微睾丸取精术(micro-TESE)并取得阳性结果(鉴定出成熟精子)的非梗阻性无精子症患者。由于浅层和深层解剖记录不全,8 名患者被排除在研究之外。研究共纳入 36 名患者,对 60 个睾丸进行了表层和深层活检。所有患者均进行了睾丸组织病理学检查,并在尝试显微 TESE 之前进行了激素评估:研究共纳入 36 名患者和 60 个睾丸。其中,47 个(78.3%)睾丸结果呈阳性。38个(63.3%)睾丸的表层TESE结果呈阳性,45个(75.0%)睾丸的深层TESE结果呈阳性。深部剥离后,SRR 提高了 13.9%。然而,两者之间并无统计学差异(P = 0.166)。根据患者的年龄、显微解剖睾丸取精侧和激素浓度,阳性取精率(从任何一侧取精)并无明显差异;这些差异在浅层或深层 TESE 之后并不明显:本文的研究结果表明,虽然深部TESE的成功率高于表层TESE,但两者并无显著的统计学差异。需要更多的证据来提供更高等级的建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Urology Annals
Urology Annals UROLOGY & NEPHROLOGY-
CiteScore
1.20
自引率
0.00%
发文量
59
审稿时长
31 weeks
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