Waterhouse-Friderichsen syndrome, septic adrenal apoplexy.

4区医学 Q3 Biochemistry, Genetics and Molecular Biology

Vitamins and Hormones Pub Date : 2024-01-01 Epub Date: 2023-11-08 DOI:10.1016/bs.vh.2023.06.001

Rishikesh Rijal, Kamal Kandel, Barun Babu Aryal, Ankush Asija, Dhan Bahadur Shrestha, Yub Raj Sedhai

引用次数: 0

Abstract

Waterhouse-Friderichsen syndrome is a rare but potentially fatal disorder of the adrenal gland characterized by bilateral adrenal hemorrhage. It is classically a result of meningococcal sepsis and presents acutely with features of shock, petechial rashes, abdominal pain, and non-specific symptoms such as headache, fatigue, and vomiting. Treatment consists of fluid resuscitation, corticosteroid replacement, and possibly surgery. The prognosis is poor despite treatment. This chapter will review the etiology, pathogenesis, clinical features, and management of the disease.

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沃特豪斯-弗里德里希森综合征，化脓性肾上腺骤停。

沃特豪斯-弗里德森综合征是一种罕见但可能致命的肾上腺疾病，以双侧肾上腺出血为特征。它通常由脑膜炎球菌败血症引起，急性期表现为休克、瘀斑皮疹、腹痛以及头痛、乏力和呕吐等非特异性症状。治疗包括液体复苏、皮质类固醇替代治疗和可能的手术治疗。尽管进行了治疗，但预后不良。本章将回顾该病的病因、发病机制、临床特征和治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Vitamins and Hormones 医学-内分泌学与代谢

CiteScore

3.80

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.