{"title":"[THE EFFICACY OF BRONCHIAL THERMOPLASTY IN LONG-TERM MAINTENANCE OF ADULT PATIENTS WITH MODERATE TO SEVERE ASTHMA].","authors":"Takahiro Matsuyama, Jun Tanaka, Kazuya Tone, Kaoruko Shimizu, Takako Nakano, Koichiro Takahashi","doi":"10.15036/arerugi.73.40","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and aims: </strong>Bronchial thermoplasty (BT) is a bronchoscopic treatment for adult patients with moderate to severe asthma. A systematic review was conducted to examine the efficacy of this treatment.</p><p><strong>Methods: </strong>Randomized controlled comparing BT to a control in adult patients with moderate to severe asthma were added to the previously conducted systematic review. Literature published prior to July 2022 was selected.</p><p><strong>Results: </strong>Four trials were included in this study. BT resulted in significant improvement in quality of life. However, no significant difference in asthma control was observed. Moreover, the incidence of severe adverse events during the treatment period was increased by BT. Furthermore, BT did not improve lung function, increase withdrawal from oral corticosteroids, reduce frequency of rescue medication usage, or increase the number of symptom-free days.</p><p><strong>Conclusion: </strong>From a risk-benefit perspective, there is insufficient evidence to support a recommendation of BT in adult patients with moderate to severe asthma.</p>","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"73 1","pages":"40-51"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Allergology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15036/arerugi.73.40","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Background and aims: Bronchial thermoplasty (BT) is a bronchoscopic treatment for adult patients with moderate to severe asthma. A systematic review was conducted to examine the efficacy of this treatment.
Methods: Randomized controlled comparing BT to a control in adult patients with moderate to severe asthma were added to the previously conducted systematic review. Literature published prior to July 2022 was selected.
Results: Four trials were included in this study. BT resulted in significant improvement in quality of life. However, no significant difference in asthma control was observed. Moreover, the incidence of severe adverse events during the treatment period was increased by BT. Furthermore, BT did not improve lung function, increase withdrawal from oral corticosteroids, reduce frequency of rescue medication usage, or increase the number of symptom-free days.
Conclusion: From a risk-benefit perspective, there is insufficient evidence to support a recommendation of BT in adult patients with moderate to severe asthma.
期刊介绍:
The Japanese Society of Allergology is made up of medical researchers and clinical physicians who share an involvement in the study of allergies and clinical immunology. Clinical subspecialties include such allergies and immune-response disorders as bronchial asthma, hypersensitivity pneumonitis, collagen disease, allergic rhinitis, pollenosis, hives, atopic dermatitis, and immunodeficiency. However, there are many patients afflicted by other allergies as well. The Society considers all such patients and disorders within its purview.