Application of Non-Ligation Technique in Thyroidectomy.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-01

Chengyu Pang, Jianming Yuan, Ru Zhou, Qiaofeng Chen, Tianxiang Wang, Weize Wu, Xunbo Huang

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引用次数: 0

Abstract

Objective: This study aimed to analyze the difference between non-ligation and traditional ligation techniques for papillary thyroid micro-carcinoma (PTMC) patients.

Methods: Patients undergoing thyroidectomy in the Department of General Surgery, Ruijin Hospital, affiliated with Shanghai Jiao Tong University, Lu Wan Branch, were retrospectively enrolled. The gender, age, operation method, operation duration, tumor size, size of thyroidectomy specimen, postoperative bleeding, drainage volume on the first postoperative day, preoperative and postoperative levels of parathyroid hormone (PTH), and blood calcium were collected.

Results: Compared with the traditional ligation technique, the non-ligation technique significantly shortened the operation time (69.36 ± 1.38 vs. 82.72 ± 2.12, P < .0001) and reached less variation of the serum calcium (2.32 ± 0.01 vs 2.28 ± 0.01, P < .001) and PTH (26.58 ± 0.08 vs 22.01 ± 1.04, P < .05) on the first postoperative day, and the above biochemical indicators returned to normal 3 weeks after surgery. The PTH in the No-ligation technique group was 7.20± 1.99, which was significantly lower than that in the Traditional ligation group (20.78± 3.78) (P < .01).

Conclusion: No-ligation technique can significantly reduce the operation time in thyroidectomy but may temporarily affect the levels of parathyroid hormone and blood calcium, and the above changes returned to normal 3 weeks after surgery. These results highlighted that No-ligation technique can benefit patients and will be a favorable treatment method.

本刊更多论文

非结扎技术在甲状腺切除术中的应用

研究目的本研究旨在分析甲状腺乳头状微癌（PTMC）患者非结扎技术与传统结扎技术的差异：方法：回顾性纳入在上海交通大学附属瑞金医院陆湾分院普外科接受甲状腺切除术的患者。收集了患者的性别、年龄、手术方式、手术时间、肿瘤大小、甲状腺切除标本大小、术后出血量、术后第一天引流量、术前和术后甲状旁腺激素（PTH）水平以及血钙：与传统结扎技术相比，非结扎技术明显缩短了手术时间（69.36 ± 1.38 vs. 82.72 ± 2.12，P < .0001），术后第一天血清钙（2.32 ± 0.01 vs. 2.28 ± 0.01，P < .001）和PTH（26.58 ± 0.08 vs. 22.01 ± 1.04，P < .05）的变化较小，术后3周上述生化指标恢复正常。免结扎技术组的 PTH 为 7.20±1.99，明显低于传统结扎技术组（20.78±3.78）（P < .01）：结论：免结扎技术可大大缩短甲状腺切除术的手术时间，但可能暂时影响甲状旁腺激素和血钙水平，术后3周上述变化恢复正常。这些结果表明，免结扎技术能使患者受益，将成为一种良好的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.