Dangers and therapeutic difficulties of intracranial hemangioma in infants: A CARE case report

IF 1.9 4区医学 Q2 OTORHINOLARYNGOLOGY

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2024-08-01 DOI:10.1016/j.anorl.2024.02.001

{"title":"Dangers and therapeutic difficulties of intracranial hemangioma in infants: A CARE case report","authors":"","doi":"10.1016/j.anorl.2024.02.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Description of neurological complications<span> induced by intracranial hemangioma in infants and by the initiation of beta-blocker treatment (propranolol).</span></p></div><div><h3>Observation</h3><p><span><span><span>A 2-month-old infant was referred for grade 5 non-congenital unilateral peripheral facial palsy. Work-up revealed ipsilateral profound hearing loss and two intracranial hemangiomas: one in the ipsilateral </span>internal auditory canal (IAC), the other in the </span>cerebellum opposite the nodule of vermis. Initial treatment with a beta-blocker (propranolol 1</span>      <span>mg/kg/day), two asthma attacks occurred, leading to initiation of fluticasone and continuation of the beta-blocker. Thirty months after discontinuation of treatment, no further progression was noted.</span></p></div><div><h3>Discussion</h3><p>Unilateral facial palsy in an infant suggests a number of diagnoses. MRI revealed IAC hemangioma. The choice of dosage and duration of treatment was based on a review of the literature and a strategy defined in multidisciplinary consultation.</p></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"141 4","pages":"Pages 227-230"},"PeriodicalIF":1.9000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Annals of Otorhinolaryngology-Head and Neck Diseases","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1879729624000188","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction

Description of neurological complications induced by intracranial hemangioma in infants and by the initiation of beta-blocker treatment (propranolol).

Observation

A 2-month-old infant was referred for grade 5 non-congenital unilateral peripheral facial palsy. Work-up revealed ipsilateral profound hearing loss and two intracranial hemangiomas: one in the ipsilateral internal auditory canal (IAC), the other in the cerebellum opposite the nodule of vermis. Initial treatment with a beta-blocker (propranolol 1 mg/kg/day for 1 month, then 3 mg/kg/day) resulted in disappearance of symptoms and regression of lesions within 8 weeks. At 20 months after introduction of maintenance therapy (propranolol 3 mg/kg/day), two asthma attacks occurred, leading to initiation of fluticasone and continuation of the beta-blocker. Thirty months after discontinuation of treatment, no further progression was noted.

Discussion

Unilateral facial palsy in an infant suggests a number of diagnoses. MRI revealed IAC hemangioma. The choice of dosage and duration of treatment was based on a review of the literature and a strategy defined in multidisciplinary consultation.

查看原文本刊更多论文

婴儿颅内血管瘤的危害和治疗困难：CARE病例报告。

简介：描述婴儿颅内血管瘤和开始使用β-受体阻滞剂（普萘洛尔）治疗引起的神经并发症：描述婴儿颅内血管瘤和开始使用β-受体阻滞剂（普萘洛尔）治疗后引起的神经系统并发症：一名 2 个月大的婴儿因 5 级非先天性单侧周围性面瘫而转诊。检查发现婴儿同侧听力严重受损，并有两个颅内血管瘤：一个位于同侧内耳道（IAC），另一个位于蚓部结节对面的小脑。最初使用β-受体阻滞剂（普萘洛尔 1 毫克/千克/天，持续 1 个月，然后 3 毫克/千克/天）治疗，结果在 8 周内症状消失，病变消退。在接受维持治疗（普萘洛尔 3 毫克/千克/天）20 个月后，哮喘发作了两次，因此开始使用氟替卡松，并继续使用β-受体阻滞剂。停止治疗 30 个月后，病情没有进一步发展：讨论：婴儿单侧面瘫有多种诊断可能。核磁共振成像显示为 IAC 血管瘤。根据文献综述和多学科会诊确定的策略，选择了治疗剂量和疗程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

European Annals of Otorhinolaryngology-Head and Neck Diseases OTORHINOLARYNGOLOGY-

CiteScore

3.70

自引率

28.00%

发文量

审稿时长

12 days

期刊介绍： European Annals of Oto-rhino-laryngology, Head and Neck diseases heir of one of the oldest otorhinolaryngology journals in Europe is the official organ of the French Society of Otorhinolaryngology (SFORL) and the the International Francophone Society of Otorhinolaryngology (SIFORL). Today six annual issues provide original peer reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches and review articles giving most up-to-date insights in all areas of otology, laryngology rhinology, head and neck surgery. The European Annals also publish the SFORL guidelines and recommendations.The journal is a unique two-armed publication: the European Annals (ANORL) is an English language well referenced online journal (e-only) whereas the Annales Françaises d’ORL (AFORL), mail-order paper and online edition in French language are aimed at the French-speaking community. French language teams must submit their articles in French to the AFORL site. Federating journal in its field, the European Annals has an Editorial board of experts with international reputation that allow to make an important contribution to communication on new research data and clinical practice by publishing high-quality articles.