Peripartum cardiomyopathy in low- and middle-income countries

IF 3.9 2区医学 Q1 OBSTETRICS & GYNECOLOGY

Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2024-02-17 DOI:10.1016/j.bpobgyn.2024.102476

Emmanuel C. Ejim , Kamilu M. Karaye , Samuel Antia , Godsent C. Isiguzo , Paschal O. Njoku

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Abstract

Peripartum cardiomyopathy (PPCM) causes pregnancy-associated heart failure, typically during the last month of pregnancy, and up to 6 months post-partum, in women without known cardiovascular disease.

PPCM is a global disease, but with a significant geographical variability within and between countries. Its true incidence in Africa is still unknown because of the lack of a PPCM population-based study. The variability in the epidemiology of PPCM between and within countries could be due to differences in the prevalence of both genetic and non-genetic risk factors.

Several risk factors have been implicated in the aetiopathogenesis of PPCM over the years.

Majority of patients with PPCM present with symptoms and signs of congestive cardiac failure.

Diagnostic work up in PPCM is prompted by strong clinical suspicion, but Echocardiography is the main imaging technique for diagnosis.

The management of PPCM involves multiple disciplines - cardiologists, anaesthetists, intensivists, obstetricians, neonatologists, and the prognosis varies widely.

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中低收入国家的围产期心肌病

围产期心肌病（PPCM）会导致与妊娠相关的心力衰竭，通常发生在妊娠的最后一个月和产后 6 个月内，发病妇女没有已知的心血管疾病。PPCM 是一种全球性疾病，但在国家内部和国家之间存在很大的地域差异。由于缺乏基于人口的 PPCM 研究，非洲的真实发病率尚不清楚。PPCM在国家之间和国家内部的流行病学差异可能是由于遗传和非遗传风险因素的流行率不同造成的。PPCM 的诊断工作由强烈的临床怀疑引起，但超声心动图是诊断的主要成像技术。PPCM 的治疗涉及多个学科--心脏病专家、麻醉师、重症监护专家、产科医生、新生儿专家，其预后差异很大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Best Practice & Research Clinical Obstetrics & Gynaecology 医学-妇产科学

CiteScore

9.40

自引率

1.80%

发文量

113

审稿时长

54 days

期刊介绍： In practical paperback format, each 200 page topic-based issue of Best Practice & Research Clinical Obstetrics & Gynaecology will provide a comprehensive review of current clinical practice and thinking within the specialties of obstetrics and gynaecology. All chapters take the form of practical, evidence-based reviews that seek to address key clinical issues of diagnosis, treatment and patient management. Each issue follows a problem-orientated approach that focuses on the key questions to be addressed, clearly defining what is known and not known. Management will be described in practical terms so that it can be applied to the individual patient.