Update on Endoscopic Treatments for Obesity.

IF 9.5 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Current Obesity Reports Pub Date : 2024-06-01 DOI:10.1007/s13679-024-00551-6

Fernanda Pessorrusso, Sagar V Mehta, Shelby Sullivan

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Abstract

Purpose of review: Increased morbidity seen with rising obesity rates continues to place an unheralded burden on our health system. Lack of higher bariatric surgery utilization and limitations with lifestyle modification and pharmacotherapy highlights the need for additional therapies for obesity. Endoscopic bariatric and metabolic therapies (EBMT) are effective, safe treatments for obesity. Current FDA-approved EBMT are confined to gastric modalities while small bowel directed therapies are still considered investigational. This review highlights current modalities of EBMT.

Recent findings: Many randomized controlled trials have been performed, including both open label and sham-controlled, which have demonstrated safety and efficacy of EBMT over lifestyle therapy alone. In addition, emerging evidence from clinical experience further supports EBMT for treatment of obesity. Current evidence supports the safety and efficacy of EBMT for obesity treatment in conjunction with lifestyle therapy. They can also be used concurrently with weight loss medications to increase total weight loss.

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肥胖症内窥镜治疗的最新进展。

审查目的：随着肥胖率的上升，发病率也随之增加，这给我们的医疗系统造成了难以承受的负担。减肥手术的使用率不高以及生活方式调整和药物疗法的局限性突出表明，我们需要更多的肥胖症疗法。内窥镜减肥和代谢疗法（EBMT）是有效、安全的肥胖症治疗方法。目前美国食品及药物管理局批准的内镜减肥和代谢疗法仅限于胃部疗法，而针对小肠的疗法仍被认为是研究性的。本综述重点介绍目前的 EBMT 方法：已进行的许多随机对照试验，包括开放标签试验和假对照试验，都证明了 EBMT 比单纯的生活方式疗法更安全、更有效。此外，来自临床经验的新证据进一步支持 EBMT 治疗肥胖症。目前的证据支持将 EBMT 与生活方式疗法结合起来治疗肥胖症的安全性和有效性。它们还可与减肥药物同时使用，以增加总的减肥效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Obesity Reports Medicine-General Medicine

CiteScore

16.40

自引率

1.10%

发文量

期刊介绍： The main objective of Current Obesity Reports is to provide expert review articles on recent advancements in the interdisciplinary field of obesity research. Our aim is to offer clear, insightful, and balanced contributions that will benefit all individuals involved in the treatment and prevention of obesity, as well as related conditions such as cardiovascular diseases, endocrine disorders, gynecological issues, cancer, mental health, respiratory complications, and rheumatological diseases. We strive to redefine the way knowledge is expressed and provide organized content for the benefit of our readership.