O. F. Kuznetsova, V. V. Orlovskaya, D. D. Vaulina, V. Yu. Obolentsev, A. S. Demyanov, R. N. Krasikova
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引用次数: 0
Abstract
An automated module for the synthesis of L-[11C-methyl]methionine, a well-known PET radiotracer for brain tumor imaging, has been designed. The module meets modern requirements for the production of radiopharmaceuticals and radiation safety; thanks to the original program created in the Delphi programming environment, module is convenient for the synthesis control (user-friendly) and operation; the service can be maintained on its own with minimal time and financial costs. The module ensures the production of L-[11C-methyl]methionine with high chemical, radiochemical and enantiomeric purity and a radiochemical yield of 30% (based on [11C]CO2 activity, not decay corrected).
期刊介绍：
Radiochemistry is a journal that covers the theoretical and applied aspects of radiochemistry, including basic nuclear physical properties of radionuclides; chemistry of radioactive elements and their compounds; the occurrence and behavior of natural and artificial radionuclides in the environment; nuclear fuel cycle; radiochemical analysis methods and devices; production and isolation of radionuclides, synthesis of labeled compounds, new applications of radioactive tracers; radiochemical aspects of nuclear medicine; radiation chemistry and after-effects of nuclear transformations.
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