Erector spinae plane block in dogs undergoing hemilaminectomy: A prospective randomized clinical trial

IF 1.4 2区农林科学 Q2 VETERINARY SCIENCES

Veterinary anaesthesia and analgesia Pub Date : 2024-02-10 DOI:10.1016/j.vaa.2024.02.002

Cristiano Bendinelli , Marianna D’Angelo , Fabio Leonardi , Natali Verdier , Francesca Cozzi , Rocco Lombardo , Diego A. Portela

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引用次数: 0

Abstract

Objective

To compare the perioperative cumulative opioid consumption and the incidence of cardiovascular complications in dogs undergoing hemilaminectomy in which either an erector spinae plane (ESP) block or systemic opioids were administered.

Study design

Prospective randomized clinical trial.

Animals

A total of 60 client-owned dogs.

Methods

Dogs were randomized to one of three groups: an ESP block (group ESP), a constant rate infusion of fentanyl (group FNT, positive control) or a single dose of methadone as premedication (group MTD, negative control). Intraoperative nociceptive response was treated with fentanyl [1 μg kg^–1, intravenously (IV)] boli. Before closure of the surgical site, morphine (0.1 mg kg^–1) was applied to the dura mater. The cumulative dose of opioids was recorded and compared between groups. The incidence of intraoperative bradycardia and/or hypotension and the time to extubation were compared between groups. The short form of the Glasgow Composite Pain Scale (SF-GCPS) was used to score nociception before anaesthetic induction and 1, 2, 6, 12,18 and 24 hours postoperatively. Methadone 0.2 mg kg^–1 was administered IV if the SF-GCPS score was ≥ 5.

Results

Group MTD required more intraoperative rescue analgesia than groups ESP (p = 0.008) and FNT (p = 0.001). The total cumulative intraoperative dose of fentanyl was higher in groups FNT (p < 0.0001) and MTD (p = 0.002) than in group ESP. The incidence of cardiovascular complications was similar between groups. Extubation time was longer in group MTD (p = 0.03). Postoperatively, the time to first rescue analgesia was longer in group ESP than in group MTD (p = 0.03). The cumulative postoperative opioid consumption and pain scores were similar between groups.

Conclusions and clinical relevance

The ESP block resulted in a reduced intraoperative opioid consumption compared with the control positive and negative groups.

查看原文本刊更多论文

对接受半椎板切除术的狗进行脊柱后凸平面阻滞：前瞻性随机临床试验

目的比较接受半椎板切除术的狗在接受竖脊平面（ESP）阻滞或全身阿片类药物治疗时围手术期阿片类药物的累积消耗量和心血管并发症的发生率。方法将狗随机分为三组：ESP阻滞组（ESP组）、恒速输注芬太尼组（FNT组，阳性对照组）或作为术前用药的单剂量美沙酮组（MTD组，阴性对照组）。术中痛觉反应由芬太尼[1 μg kg-1，静脉注射（IV）]治疗。关闭手术部位前，在硬脑膜上注射吗啡（0.1 毫克/千克）。记录阿片类药物的累积剂量，并进行组间比较。比较各组术中心动过缓和/或低血压的发生率以及拔管时间。在麻醉诱导前以及术后 1、2、6、12、18 和 24 小时内，使用格拉斯哥综合疼痛量表（SF-GCPS）简表对痛觉进行评分。如果 SF-GCPS 评分≥5，则静脉注射美沙酮 0.2 mg kg-1。结果 MTD 组比 ESP 组（p = 0.008）和 FNT 组（p = 0.001）需要更多的术中镇痛抢救。FNT 组（p = 0.0001）和 MTD 组（p = 0.002）的术中芬太尼累积总剂量高于 ESP 组。两组心血管并发症的发生率相似。MTD 组拔管时间更长（p = 0.03）。术后，ESP 组首次镇痛抢救时间长于 MTD 组（p = 0.03）。结论和临床意义与对照阳性组和阴性组相比，ESP阻滞可减少术中阿片类药物的用量。

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来源期刊

Veterinary anaesthesia and analgesia 农林科学-兽医学

CiteScore

3.10

自引率

17.60%

发文量

审稿时长

97 days

期刊介绍： Veterinary Anaesthesia and Analgesia is the official journal of the Association of Veterinary Anaesthetists, the American College of Veterinary Anesthesia and Analgesia and the European College of Veterinary Anaesthesia and Analgesia. Its purpose is the publication of original, peer reviewed articles covering all branches of anaesthesia and the relief of pain in animals. Articles concerned with the following subjects related to anaesthesia and analgesia are also welcome: the basic sciences; pathophysiology of disease as it relates to anaesthetic management equipment intensive care chemical restraint of animals including laboratory animals, wildlife and exotic animals welfare issues associated with pain and distress education in veterinary anaesthesia and analgesia. Review articles, special articles, and historical notes will also be published, along with editorials, case reports in the form of letters to the editor, and book reviews. There is also an active correspondence section.