Combined factor VIII and IX deficiency: An exceptional case

Iffat Jamal, Ahmed Kamran Jeelani
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Abstract

Familial multiple coagulation factor deficiencies are a group of rare inherited disorders that are characterized by the simultaneous decrease in the levels of two or more coagulation factors. Common synchronous deficiencies are factors VIII and IX and combined deficiency of Vitamin K-dependent coagulation factors (factors II, VII, IX, and X). Here, we report a case of synchronous dual deficiency of factor VIII and IX, which is an extremely rare occurrence and no case report has been mentioned so far to the best of our knowledge. Recognizing such a dual deficiency is very important for proper management of patients.
第八因子和第九因子合并缺乏症:一个特殊病例
家族性多种凝血因子缺乏症是一组罕见的遗传性疾病,其特征是两种或两种以上凝血因子的水平同时下降。常见的同步缺乏症是第八因子和第九因子,以及维生素 K 依赖性凝血因子(第二、第七、第九和第十因子)的合并缺乏症。在此,我们报告了一例因子 VIII 和 IX 同步双重缺乏症病例,据我们所知,这种情况极为罕见,迄今为止尚未有任何病例报告。识别这种双重缺乏症对患者的正确治疗非常重要。
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