PAINLESS NEURALGIC AMYOTROPHY (PARSONAGE-TURNER SYNDROME) – A CASE REPORT

Veronika Vasileva, Plamen G. Stoev, M. Danovska, I. Mladenovski, E. Ovcharova, Emil Simeonov
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Abstract

Background: Neuralgic amyotrophy (NA) is a rare disorder typically characterized by an abrupt onset of upper extremity pain followed by progressive muscle weakness, atrophy and occasional sensory loss. Although NA has been hypothesized to be an autoimmune-mediated disorder. It is considered a primarily clinical diagnosis, electrodiagnostic evaluation is essential for the diagnosis confirmation and can exclude other etiologies. Electrodiagnostic findings can reveal patchy damage to any nerve within the brachial plexus. Case Description: In the current case report, we are presenting a 43-years-old man admitted to the Neurology Department of “UMHAT Dr. Georgi Stranski” in Pleven, Bulgaria, with decreased muscle strength and limited active movements in the left upper shoulder for approximately 3 weeks. The patient denied feeling any pain during the onset and afterwards. He had no previous infections, vaccinations and history of other diseases. The detailed neurological examination showed the left upper extremity decreased antigravity strength in the deltoid and infraspinatus muscles with marked atrophy of the same. Hyporeflexia of the left biceps and brachioradialis deep‐tendon reflexes was present. Electromyography findings showed denervation of the deltoid and infraspinatus muscles. Initial reinnervation of supraspinatus and cervical paraspinal muscles was present. The diagnosis of NA was confirmed by both the neurological examination and the electrophysiological findings. Conclusion: We are presenting a clinical case of idiopathic neuralgic amyotrophy with atypical painless presentation and discussing the most significant aspects of the disorder with regards to the difficulties in approaching the correct diagnosis. A better understanding of the NA clinical symptoms and signs variability improves the diagnostic and therapeutic approach.
无痛性神经性肌萎缩症(帕森纳-特纳综合征)--病例报告
背景:神经性肌萎缩症(NA)是一种罕见的疾病,其典型特征是突然出现上肢疼痛,随后出现进行性肌肉无力、萎缩和偶尔感觉丧失。尽管 NA 被认为是一种由自身免疫介导的疾病,但临床诊断主要是通过电生理诊断。它主要是一种临床诊断,但电诊断评估对确诊至关重要,可排除其他病因。电诊断结果可显示臂丛内任何神经的斑片状损伤。病例描述在本病例报告中,我们介绍的是一名 43 岁的男子,因左肩上部肌肉力量下降和主动活动受限约 3 周,入住保加利亚普列文 "UMHAT Georgi Stranski 医生 "神经科。患者否认在发病期间和之后感到任何疼痛。他以前没有感染、接种过疫苗,也没有其他疾病史。详细的神经系统检查显示,患者左上肢三角肌和冈下肌抗重力能力下降,并出现明显萎缩。左侧肱二头肌和肱肌深腱反射减弱。肌电图检查结果显示三角肌和冈下肌失神经支配。冈上肌和颈椎旁肌肉出现初步神经支配。神经系统检查和电生理检查结果均证实了 NA 的诊断。结论我们介绍了一例表现为非典型无痛的特发性神经痛性肌萎缩症的临床病例,并讨论了该疾病最重要的方面,以及正确诊断的困难。更好地了解特发性神经痛性肌萎缩症的临床症状和体征变异性,有助于改进诊断和治疗方法。
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