Saeeda Gul, Ehtsham Azhar, Iftikhar Ahmed, Muhammad Jamal
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引用次数: 0
Abstract
The increasing incidence of Chikungunya virus (CHIKV) as an important public health issue led to the investigation of novel approaches to disease control. In this study, we analyze Chikungunya epidemic model in the presence of Wolbachia-infected mosquitoes, which is a promising biological approach for controlling vector-borne diseases. The basic reproduction number ([Formula: see text]) of the proposed model is calculated using the next generation matrix approach. In this study, we utilize a hybrid methodology that combines the genetic algorithm (GA) and interior point algorithm (IPA) to numerically solve the proposed Chikungunya epidemic model. Our investigation examines the impact of key parameters, such as biting rate, reproduction rate, mortality rate, and transmission probability, on the complex dynamics of disease classes. This analysis provides valuable insights into the transmission dynamics of Chikungunya and highlights the potential effectiveness of interventions based on Wolbachia. We conclude that the numerical findings produced using the hybrid GA and IPA are in good agreement with those obtained using the traditional fourth-order Runge–Kutta (RK4) approach.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.