Lymphoma presenting as a parapharyngeal space tumour

M. M. Mohamed, K. D. R. A. Kirihena
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Abstract

Among all head and neck tumours, approximately 0.5% to 0.8% localize in the parapharyngeal space, with Non-Hodgkin’s lymphomas in this region being exceptionally rare. They are documented in the literature either as isolated cases or in small case series. Here, we present a case involving a middle aged man who exhibited 4 month history of dysphagia and hoarse voice. Upon examination, showed a bulged left side of the soft palate and medialization of the pharyngeal wall. CT and MRI revealed a large lesion in the left parapharyngeal region pushing the pharynx anteromedially. Similar intensity enhancing lesion noted in nasopharynx. A transoral excision of parapharyngeal mass was performed, revealing a large B-cell non-Hodgkin’s lymphoma. Typically, parapharyngeal space tumours are benign, and surgery is the preferred treatment. Patient was transferred to tertiary care oncology hospital for further treatment. This case underscores the rarity but potential presence of extranodal non-Hodgkin’s lymphomas in the head and neck. Recognizing this pathology is crucial due to the different treatment approach it necessitates.
表现为咽旁间隙肿瘤的淋巴瘤
在所有头颈部肿瘤中,约有0.5%至0.8%的肿瘤位于咽旁间隙,而位于该区域的非霍奇金淋巴瘤则异常罕见。在文献中,这些淋巴瘤要么是孤立病例,要么是小型病例系列。在此,我们介绍一例病例,患者为一名中年男子,有 4 个月的吞咽困难和声音嘶哑病史。经检查,患者左侧软腭隆起,咽壁内侧化。CT 和 MRI 显示,左侧咽旁区域有一个巨大病灶,将咽部推向前内侧。鼻咽部也发现了类似的强化病灶。对咽旁肿块进行了经口切除术,发现是一个大的B细胞非霍奇金淋巴瘤。咽旁间隙肿瘤通常为良性,手术是首选治疗方法。患者被转到三级肿瘤医院接受进一步治疗。本病例强调了头颈部结节外非霍奇金淋巴瘤的罕见性和潜在性。由于需要采取不同的治疗方法,因此认识这种病理学至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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