Recent advances of sesquiterpenoid dimers from Compositae: distribution, chemistry and biological activities

IF 7.3 2区 生物学 Q1 PLANT SCIENCES
FanCheng Meng, Zhe Wang, SiJie Peng, GangGang Zhou, Ammara Khalid, JingXin Mao, GuoWei Wang, ZhiHua Liao, Min Chen
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Abstract

Composite family contains a wide variety of plants and many of them possess high medicinal value. Various constituents have been isolated from members of Composite family. Sesquiterpenoids prove to be the characteristic constituents. In recent years, phytochemical studies on natural sesquiterpenoids, especially the sesquiterpenoid dimers from Composite have been a hot spot. As an important class of bioactive natural products, about 260 novel sesquiterpenoid dimers were isolated from plants of Compositae family since 2018 till date and most of them displayed significant therapeutic potential including anti-inflammatory, anti-tumor, neuroprotective, and other effects. In this review, the structural features, plant resources, and biological activities of these newly discovered sesquiterpenoid dimers were summarized.

Graphical abstract

Abstract Image

菊科倍半萜二聚体的最新进展:分布、化学和生物活性
复合科植物种类繁多,其中许多具有很高的药用价值。从复合科植物中分离出了多种成分。倍半萜类化合物被证明是其特征成分。近年来,有关天然倍半萜类化合物,尤其是复合类倍半萜二聚体的植物化学研究成为热点。作为一类重要的生物活性天然产物,自2018年至今,从复合类植物中分离出约260种新型倍半萜二聚体,其中大部分显示出显著的治疗潜力,包括抗炎、抗肿瘤、神经保护等作用。本综述总结了这些新发现的倍半萜二聚体的结构特征、植物资源和生物活性。
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来源期刊
Phytochemistry Reviews
Phytochemistry Reviews PLANT SCIENCES-
CiteScore
16.30
自引率
2.60%
发文量
54
审稿时长
2 months
期刊介绍: Phytochemistry Reviews is the sole review journal encompassing all facets of phytochemistry. It publishes peer-reviewed papers in six issues annually, including topical issues often stemming from meetings organized by the Phytochemical Society of Europe. Additionally, the journal welcomes original review papers that contribute to advancing knowledge in various aspects of plant chemistry, function, biosynthesis, effects on plant and animal physiology, pathology, and their application in agriculture and industry. Invited meeting papers are supplemented with additional review papers, providing a comprehensive overview of the current status across all areas of phytochemistry.
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