{"title":"Organic encapsulants for bioresorbable medical electronics","authors":"Junhak Lee, Sunho Park, Yeonsik Choi","doi":"10.1557/s43577-023-00652-y","DOIUrl":null,"url":null,"abstract":"<p>Bioresorbable medical electronics represents an emerging class of implantable sensors and/or stimulators that can be absorbed harmlessly in the human body, eliminating the patients’ permanent loads and the needs for risky secondary removal surgeries. This article specifically highlights recent advances in organic encapsulans that govern the lifetime, mechanical and electrical stability of the bioresorbable electronic implants. The core content focuses on the physics and chemistry of bioresorbable polymers, spanning degradation mechanism, mechanical stretchablilty, water permeability, and interfacial adhesiveness, along with tissue adhesion. Following discussions highlight the use cases of these polymers as organic encapsulations in bioresorbable electronic implants with therapeutic purposes, including nerve regeneration, pain block, and temporary cardiac pacing. A concluding section summarizes research opportunities of organic materials for advanced bioresorbable electronic systems.</p><h3 data-test=\"abstract-sub-heading\">Graphical Abstract</h3>\n","PeriodicalId":18828,"journal":{"name":"Mrs Bulletin","volume":"73 1","pages":""},"PeriodicalIF":4.1000,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mrs Bulletin","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1557/s43577-023-00652-y","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Bioresorbable medical electronics represents an emerging class of implantable sensors and/or stimulators that can be absorbed harmlessly in the human body, eliminating the patients’ permanent loads and the needs for risky secondary removal surgeries. This article specifically highlights recent advances in organic encapsulans that govern the lifetime, mechanical and electrical stability of the bioresorbable electronic implants. The core content focuses on the physics and chemistry of bioresorbable polymers, spanning degradation mechanism, mechanical stretchablilty, water permeability, and interfacial adhesiveness, along with tissue adhesion. Following discussions highlight the use cases of these polymers as organic encapsulations in bioresorbable electronic implants with therapeutic purposes, including nerve regeneration, pain block, and temporary cardiac pacing. A concluding section summarizes research opportunities of organic materials for advanced bioresorbable electronic systems.
期刊介绍：
MRS Bulletin is one of the most widely recognized and highly respected publications in advanced materials research. Each month, the Bulletin provides a comprehensive overview of a specific materials theme, along with industry and policy developments, and MRS and materials-community news and events. Written by leading experts, the overview articles are useful references for specialists, but are also presented at a level understandable to a broad scientific audience.
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