“Spaceflight-to-Eye Clinic”: Terrestrial advances in ophthalmic healthcare delivery from space-based innovations

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Joshua Ong , Ethan Waisberg , Mouayad Masalkhi , Alex Suh , Sharif Amit Kamran , Phani Paladugu , Prithul Sarker , Nasif Zaman , Alireza Tavakkoli , Andrew G. Lee
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Abstract

The phrase “Bench-to-Bedside” is a well-known phrase in medicine, highlighting scientific discoveries that directly translate to impacting patient care. Key examples of translational research include identification of key molecular targets in diseases and development of diagnostic laboratory tests for earlier disease detection. Bridging these scientific advances to the bedside/clinic has played a meaningful impact in numerous patient lives. The spaceflight environment poses a unique opportunity to also make this impact; the nature of harsh extraterrestrial conditions and medically austere and remote environments push for cutting-edge technology innovation. Many of these novel technologies built for the spaceflight environment also have numerous benefits for human health on Earth. In this manuscript, we focus on “Spaceflight-to-Eye Clinic” and discuss technologies built for the spaceflight environment that eventually helped to optimize ophthalmic health on Earth (e.g., LADAR for satellite docking now utilized in eye-tracking technology for LASIK). We also discuss current technology research for spaceflight associated neuro-ocular syndrome (SANS) that may also be applied to terrestrial ophthalmic health. Ultimately, various advances made to enable to the future of space exploration have also advanced the ophthalmic health of individuals on Earth.

"从太空飞行到眼科诊所":天基创新在眼科医疗服务方面取得的地面进展
在医学界,"从实验室到临床"(Bench-to-Bedside)是一个众所周知的短语,强调的是直接转化为影响患者护理的科学发现。转化研究的主要例子包括确定疾病的关键分子靶点和开发用于早期疾病检测的实验室诊断测试。将这些科学进步与床边/临床相结合,对无数病人的生活产生了重大影响。航天环境也为产生这种影响提供了独特的机会;恶劣的地外条件和艰苦偏远的医疗环境推动了尖端技术的创新。这些为航天环境打造的新技术中,有许多也能为地球上的人类健康带来诸多益处。在本手稿中,我们将重点关注 "太空飞行到眼科诊所",并讨论为太空飞行环境而开发的技术,这些技术最终帮助优化了地球上的眼科健康(例如,用于卫星对接的激光雷达现在被用于 LASIK 的眼球跟踪技术)。我们还讨论了目前针对太空飞行相关神经眼综合症(SANS)的技术研究,这些技术也可应用于地面眼科健康。最终,为未来太空探索所取得的各种进步也促进了地球上人们的眼科健康。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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