A case of prosthetic joint infection due to the rare opportunist yeast, Cyberlindnera fabianii.

Q3 Medicine

Current Medical Mycology Pub Date : 2023-09-01 DOI:10.22034/CMM.2023.345063.1418

Nurhafiza Ishak, Kallaivani Pachayappan, Chu Lee Hwa, Muhammad Asyraf Mohamad Kamil

{"title":"A case of prosthetic joint infection due to the rare opportunist yeast, Cyberlindnera fabianii.","authors":"Nurhafiza Ishak, Kallaivani Pachayappan, Chu Lee Hwa, Muhammad Asyraf Mohamad Kamil","doi":"10.22034/CMM.2023.345063.1418","DOIUrl":null,"url":null,"abstract":"Background and purpose: Invasive fungal infections caused by Cyberlindnera fabianii (Cy. fabianii) have recently increased despite the low virulence potential of this yeast. However, limited information about the widely-used commercial biochemical identification systems has led to an underestimation of Cy. fabianii infections in clinical settings.Case report: This study reports a case of prosthetic joint infection in a patient who had a previous history of total knee replacement surgery. Cy. fabianii was recovered from intraoperative culture specimens identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and confirmed using molecular assays. It was, however, initially misidentified as Candida utilis by phenotypic identification.Conclusion: Due to the emergence of uncommon yeast species, it is important to accurately identify and perform antifungal susceptibility testing on uncommon yeast isolates for appropriate management.","PeriodicalId":10863,"journal":{"name":"Current Medical Mycology","volume":"9 3","pages":"45-49"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10864742/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Medical Mycology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22034/CMM.2023.345063.1418","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Background and purpose: Invasive fungal infections caused by Cyberlindnera fabianii (Cy. fabianii) have recently increased despite the low virulence potential of this yeast. However, limited information about the widely-used commercial biochemical identification systems has led to an underestimation of Cy. fabianii infections in clinical settings.

Case report: This study reports a case of prosthetic joint infection in a patient who had a previous history of total knee replacement surgery. Cy. fabianii was recovered from intraoperative culture specimens identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and confirmed using molecular assays. It was, however, initially misidentified as Candida utilis by phenotypic identification.

Conclusion: Due to the emergence of uncommon yeast species, it is important to accurately identify and perform antifungal susceptibility testing on uncommon yeast isolates for appropriate management.

查看原文本刊更多论文

一例由罕见的机会主义酵母菌 Cyberlindnera fabianii 引起的假体关节感染病例。

背景和目的：尽管Cyberlindnera fabianii（Cy. fabianii）酵母菌的致病力很低，但由这种酵母菌引起的侵袭性真菌感染近来有所增加。然而，由于广泛使用的商业生化鉴定系统的相关信息有限，导致临床环境中对法比亚酵母菌感染的估计不足：本研究报告了一例人工关节感染病例，患者曾接受过全膝关节置换手术。通过基质辅助激光解吸附/电离飞行时间质谱法鉴定并使用分子检测法确认了从术中培养标本中回收的法比亚农杆菌。然而，通过表型鉴定，它最初被误认为是utilis念珠菌：结论：由于不常见酵母菌种类的出现，准确鉴定不常见酵母菌分离物并对其进行抗真菌药敏试验以进行适当处理非常重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊