The effect of maternal weight on neonatal cardiac functions following diabetic and non-diabetic pregnancies.

Northern clinics of Istanbul Pub Date : 2024-01-26 eCollection Date: 2024-01-01 DOI:10.14744/nci.2023.03342

Elif Erolu, Ozlem Sahin, Leyla Bilgin, Mehmet Karacan, Figen Akalin

{"title":"The effect of maternal weight on neonatal cardiac functions following diabetic and non-diabetic pregnancies.","authors":"Elif Erolu, Ozlem Sahin, Leyla Bilgin, Mehmet Karacan, Figen Akalin","doi":"10.14744/nci.2023.03342","DOIUrl":null,"url":null,"abstract":"Objective: We aimed to study myocardial functions of infants appropriate and large for gestational age (IDM-AGA, IDM-LGA) of diabetic mothers (IDM) and AGA and LGA infants of non-diabetic mothers comparatively.Methods: Newborns were assessed between 24 and 72 h. M-Mode, pulsed wave, and tissue Doppler echocardiography were performed.Results: A negative correlation was found between shortening fraction and maternal weight at delivery in the LGA group (p=0.009, r=-0.58). E/Early diastolic (E') ratio and deceleration time were increased in IDM-AGA than AGA group (p=0.02, p=0.02). There was a negative correlation between maternal blood glucose and E/A ratio (p=0.015 r=-0.63), a positive correlation between maternal blood glucose and mitral A, late diastolic (A') wave in IDM-AGA (p=0.014 r=0.63, p=0.016 r=0.62). Maternal weight gain during pregnancy was in correlation with measured and tei index in IDM-AGA group (p=0.008 r=0.72). Maternal age, pre-pregnancy weight, and weight at delivery and mitral E were higher in IDM-LGA group than IDM-AGA (p=0.03, p=0.01, p=0.003, p=0.012).Conclusion: We found that maternal weight has a negative effect on myocardial function in LGA newborns. Diastolic functions were found impaired in IDM-AGA infants and in infants of mothers with high blood glucose. Maternal weight gain during pregnancy has a negative effect on myocardial functions.","PeriodicalId":94347,"journal":{"name":"Northern clinics of Istanbul","volume":"11 1","pages":"60-65"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861430/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Northern clinics of Istanbul","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14744/nci.2023.03342","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: We aimed to study myocardial functions of infants appropriate and large for gestational age (IDM-AGA, IDM-LGA) of diabetic mothers (IDM) and AGA and LGA infants of non-diabetic mothers comparatively.

Methods: Newborns were assessed between 24 and 72 h. M-Mode, pulsed wave, and tissue Doppler echocardiography were performed.

Results: A negative correlation was found between shortening fraction and maternal weight at delivery in the LGA group (p=0.009, r=-0.58). E/Early diastolic (E') ratio and deceleration time were increased in IDM-AGA than AGA group (p=0.02, p=0.02). There was a negative correlation between maternal blood glucose and E/A ratio (p=0.015 r=-0.63), a positive correlation between maternal blood glucose and mitral A, late diastolic (A') wave in IDM-AGA (p=0.014 r=0.63, p=0.016 r=0.62). Maternal weight gain during pregnancy was in correlation with measured and tei index in IDM-AGA group (p=0.008 r=0.72). Maternal age, pre-pregnancy weight, and weight at delivery and mitral E were higher in IDM-LGA group than IDM-AGA (p=0.03, p=0.01, p=0.003, p=0.012).

Conclusion: We found that maternal weight has a negative effect on myocardial function in LGA newborns. Diastolic functions were found impaired in IDM-AGA infants and in infants of mothers with high blood glucose. Maternal weight gain during pregnancy has a negative effect on myocardial functions.

查看原文本刊更多论文

糖尿病和非糖尿病孕妇体重对新生儿心脏功能的影响。

研究目的我们旨在研究糖尿病母亲（IDM）所生的胎龄适中婴儿和胎龄偏大婴儿（IDM-AGA、IDM-LGA）与非糖尿病母亲所生的AGA婴儿和LGA婴儿的心肌功能比较：方法：对 24 至 72 小时内的新生儿进行评估，并进行 M 型、脉冲波和组织多普勒超声心动图检查：结果：在 LGA 组中，缩短率与产妇分娩时的体重呈负相关（P=0.009，r=-0.58）。IDM-AGA组的E/早期舒张压（E'）比值和减速时间比AGA组增加（p=0.02，p=0.02）。母体血糖与 E/A 比值呈负相关（p=0.015 r=-0.63），IDM-AGA 组母体血糖与二尖瓣 A 波、舒张晚期（A'）波呈正相关（p=0.014 r=0.63，p=0.016 r=0.62）。在 IDM-AGA 组中，孕妇孕期体重增加与测量值和 tei 指数相关（p=0.008 r=0.72）。IDM-LGA组产妇年龄、孕前体重、分娩时体重和二尖瓣E均高于IDM-AGA组（P=0.03、P=0.01、P=0.003、P=0.012）：我们发现，产妇体重对 LGA 新生儿的心肌功能有负面影响。IDM-AGA婴儿和高血糖母亲的婴儿舒张功能受损。孕期母体体重增加对心肌功能有负面影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Northern clinics of Istanbul

自引率

0.00%

发文量