Initial evidence of the acute effect of electronic nicotine delivery system use on energy intake.

IF 2.4 3区 医学 Q3 PHARMACOLOGY & PHARMACY
Experimental and clinical psychopharmacology Pub Date : 2024-08-01 Epub Date: 2024-02-15 DOI:10.1037/pha0000710
Gabrielle T Maldonado, Christoph Höchsmann, Akansha Anbil, Karissa Neubig, Rabia Imran, Bernard F Fuemmeler, Thokozeni Lipato, Vineela Rachagiri, Andrew J Barnes, Corby K Martin, Caroline O Cobb
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引用次数: 0

Abstract

Previous work has aimed to disentangle the acute effects of nicotine and smoking on appetite with mixed findings. Electronic nicotine delivery systems (ENDS) have yet to be examined in this regard despite evidence of use for weight control. The present study tested the influence of an ENDS on acute energy intake and associated subjective effects. Participants (n = 34; 18-65 years) with current ENDS use completed two randomly ordered clinical lab sessions after overnight abstinence from tobacco/nicotine/food/drinks (other than water). Sessions differed by the product administered over 20 min: active (20 puffs of a JUUL ENDS device; 5% nicotine tobacco-flavored pod) or control (access to an uncharged JUUL with an empty pod). About 40 min after product administration, participants were provided an ad lib buffet-style meal with 21 food/drink items. Subjective ratings were assessed at baseline, after product use, and before/after the meal. Energy intake (kcal) was calculated using pre-post buffet item weights. Repeated measures analyses of variance and pairwise comparisons were used to detect differences by condition and time (α < .05). Mean ± standard error of the mean energy intake did not differ significantly between active (1011.9 ± 98.8 kcal) and control (939.8 ± 88.4 kcal; p = .108) conditions. Nicotine abstinence symptoms significantly decreased after the active condition, while satiety significantly increased. Following the control condition, satiety remained constant while hunger significantly increased relative to baseline. Findings indicate that acute ENDS use did not significantly impact energy intake, but there was an ENDS-associated subjective increase in satiety and relative decrease in hunger. Results support further investigation of ENDS on appetite. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

使用电子尼古丁输送系统对能量摄入产生急性影响的初步证据。
以往的研究旨在厘清尼古丁和吸烟对食欲的急性影响,结果不一。尽管有证据表明电子尼古丁给药系统(ENDS)可用于控制体重,但尚未在这方面进行研究。本研究测试了ENDS对急性能量摄入的影响以及相关的主观效应。目前使用ENDS的参与者(n = 34;18-65 岁)在一夜禁烟/禁酒/禁食/禁饮(水除外)后完成了两次随机排序的临床实验。在 20 分钟内使用的产品不同:主动型(使用 JUUL ENDS 装置吸 20 口;5% 尼古丁烟草味 pod)或对照型(使用未充电的 JUUL 和空 pod)。在服用产品约 40 分钟后,参与者可随意享用自助餐,其中包括 21 种食物/饮料。分别在基线、使用产品后以及餐前/餐后进行主观评分。能量摄入量(千卡)根据用餐前/后自助餐项目的权重进行计算。采用重复测量方差分析和配对比较来检测不同条件和时间的差异(α < .05)。能量摄入的平均值(标准误差)在活动状态(1011.9 ± 98.8 千卡)和控制状态(939.8 ± 88.4 千卡;p = .108)之间没有显著差异。在积极状态下,尼古丁戒断症状明显减轻,而饱腹感则明显增加。在对照组条件下,饱腹感保持不变,而饥饿感相对于基线则明显增加。研究结果表明,急性使用ENDS不会对能量摄入产生显著影响,但ENDS相关的饱腹感会主观增加,而饥饿感会相对减少。研究结果支持进一步调查ENDS对食欲的影响。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.20
自引率
8.70%
发文量
164
审稿时长
6-12 weeks
期刊介绍: Experimental and Clinical Psychopharmacology publishes advances in translational and interdisciplinary research on psychopharmacology, broadly defined, and/or substance abuse.
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