High-intensity interval training in individuals with posttraumatic stress disorder: A randomized controlled pilot trial

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Nikola Schoofs , Anima Pieper , Kristina Meyer , Sarah Herrmann , Annabell Jäger , Felix Wülfing , Maximilian Grummt , Bernd Wolfarth , Andreas Ströhle , Kathlen Priebe
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Abstract

Background

Exercise interventions have become more important in the treatment of mental disorders. High-intensity interval training (HIIT) has achieved promising results in the treatment of different mental disorders, like depression or panic disorder. To our knowledge, no study investigated the efficacy of HIIT as a sole treatment in a sample of individuals with fully diagnosed PTSD.

Methods

40 participants with PTSD were randomized to either HIIT or a control group (low intensity training, LIT). They underwent a 12-day training period. The primary outcome were PTSD symptoms as assessed by the Clinician-Administered PTSD Scale (CAPS). Secondary outcome were self-reported posttraumatic, depressive and dissociative symptoms and overall psychological distress assessed at baseline, post treatment (one week after training) and follow up (six weeks post treatment). We used linear mixed models to assess the differential effects of the two trainings on clinical symptoms.

Results

In both HIIT and LIT group, clinician- and self-rated PTSD symptom severity as well as depressive and dissociative symptoms and overall psychological distress decreased significantly from baseline to follow up with medium effect sizes related to PTSD symptomatology (Cohen’s d = 0.76, p < .001) and small effect sizes related to depressive (Cohen’s d = 0.45, p < .001), dissociative symptoms (Cohen’s d = 0.42, p < .001) and overall psychological distress (Cohen’s d = 0.43, p < .001). There were no differences in symptom change between groups.

Conclusion

In our pilot study, HITT did not seem to be superior to LIT in a sample of individuals with PTSD.

创伤后应激障碍患者的高强度间歇训练:随机对照试验
背景运动干预在精神障碍的治疗中变得越来越重要。高强度间歇训练(HIIT)在治疗不同的精神障碍(如抑郁症或恐慌症)方面取得了可喜的成果。据我们所知,还没有一项研究调查了高强度间歇训练作为唯一治疗方法对完全确诊的创伤后应激障碍患者的疗效。他们接受了为期 12 天的训练。主要结果是由临床医师管理的创伤后应激障碍量表(CAPS)评估的创伤后应激障碍症状。次要结果是在基线、治疗后(训练后一周)和随访(治疗后六周)评估的自我报告的创伤后症状、抑郁症状和分离症状以及总体心理困扰。我们使用线性混合模型来评估两种训练对临床症状的不同影响。结果在 HIIT 和 LIT 组中,临床医生和自我评定的创伤后应激障碍症状严重程度、抑郁和分离症状以及总体心理压力从基线到随访均显著下降,与创伤后应激障碍症状相关的效应大小为中等(Cohen's d = 0.76,p <.001),与抑郁症状(Cohen's d = 0.45,p <.001)、分离症状(Cohen's d = 0.42,p <.001)和总体心理困扰(Cohen's d = 0.43,p <.001)相关的小效应量。结论在我们的试点研究中,在创伤后应激障碍患者样本中,HITT 似乎并不优于 LIT。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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