Idiopathic terminal ileitis: myth or true entity?

IF 2.6 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Current Opinion in Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-02-14 DOI:10.1097/MOG.0000000000001011

Nicoletta Nandi, Foong Way David Tai, Mark McAlindon, Reena Sidhu

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引用次数: 0

Abstract

Purpose of review: Isolated terminal ileitis is an increasing phenomenon identified during colonoscopy. Idiopathic terminal ileitis (IDTI) is a diagnosis of exclusion, representing a significant challenge from a diagnostic and management point of view. This review provides an overview of the most recent and relevant evidence on idiopathic IDTI, focusing on its evolution, the natural history and the management strategies proposed in the literature.

Recent findings: IDTI is uncommon, with a reported prevalence between 0.5 and 7%. The main differential is with Crohn's disease and intestinal tuberculosis in endemic countries. A proportion of patients (0-50%) can progress and develop Crohn's disease; however, there are no reliable predictive factors to stratify IDTI patients.

Summary: IDTI is a challenging entity, with a small proportion of patients progressing to Crohn's disease over time thus requiring follow-up. Noninvasive modalities such as capsule endoscopy are useful for follow-up, but further research is required to better understand this entity.

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特发性末端回肠炎：传说还是真实存在？

审查目的：在结肠镜检查中发现的孤立性末端回肠炎现象越来越多。特发性末端回肠炎（IDTI）是一种排除性诊断，从诊断和管理的角度来看是一项重大挑战。本综述概述了特发性回肠末端炎的最新相关证据，重点关注其演变、自然史以及文献中提出的治疗策略：特发性 IDTI 并不常见，据报道发病率在 0.5% 到 7% 之间。在疾病流行的国家，主要与克罗恩病和肠结核相鉴别。有一部分患者（0-50%）会发展为克罗恩病；但是，目前还没有可靠的预测因素对 IDTI 患者进行分层。总结：IDTI 是一种具有挑战性的疾病，一小部分患者会随着时间的推移发展为克罗恩病，因此需要进行随访。胶囊内镜等无创方式有助于随访，但要更好地了解这种疾病还需要进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Gastroenterology 医学-胃肠肝病学

CiteScore

5.30

自引率

0.00%

发文量

137

审稿时长

6-12 weeks

期刊介绍： Published bimonthly and offering a unique and wide ranging perspective on the key developments in the field, each issue of Current Opinion in Gastroenterology features hand-picked review articles from our team of expert editors. With twelve disciplines published across the year – including gastrointestinal infections, nutrition and inflammatory bowel disease – every issue also contains annotated references detailing the merits of the most important papers.