The landscape of fetus metabolism in maternal hyperglycemia.

IF 11.4 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Trends in Endocrinology and Metabolism Pub Date : 2024-04-01 Epub Date: 2024-02-09 DOI:10.1016/j.tem.2024.01.012

Miranda E Kelly, Thomas F Martinez, Cholsoon Jang

引用次数: 0

Abstract

Maternal hyperglycemia contributes to abnormal fetal development; yet, how it affects fetal metabolism is poorly understood. Perez-Ramirez and colleagues recently provided a comprehensive metabolic atlas of fetal organs isolated from normal and diabetic pregnant mice, identifying novel metabolites and alterations in tissue glucose utilization throughout mid-to-late gestation by maternal hyperglycemia.

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母体高血糖时胎儿的新陈代谢状况。

母体高血糖会导致胎儿发育异常；然而，人们对高血糖如何影响胎儿代谢却知之甚少。Perez-Ramirez 及其同事最近提供了一个从正常怀孕小鼠和糖尿病怀孕小鼠中分离出来的胎儿器官的综合代谢图谱，确定了新的代谢物以及母体高血糖在整个妊娠中晚期对组织葡萄糖利用的改变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Endocrinology and Metabolism 医学-内分泌学与代谢

CiteScore

20.10

自引率

0.00%

发文量

审稿时长

82 days

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