Comorbid Conditions Are Associated With Cognitive Impairment in Native Hawaiians and Pacific Islanders.

IF 1.2 4区医学 Q3 GERONTOLOGY

International Journal of Aging & Human Development Pub Date : 2024-12-01 Epub Date: 2024-02-07 DOI:10.1177/00914150241231186

Archana J McEligot, Ka'ala Pang, Sabrina Moran-Gomez, Sinjini Mitra, Mariella Santos, Zahra Tahmasebi, Sanam Kazemi

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引用次数: 0

Abstract

We examined the association between comorbid conditions and mild cognitive impairment (MCI) in Native Hawaiians and Pacific Islanders (NHPI) (n = 54). Cross-sectional, self-reported questionnaires were utilized to collect demographic, comorbid conditions, and MCI (via the AD8 index) data. Separate logistic regression models were conducted to investigate the relationship between comorbid conditions and MCI, adjusting for other covariates. We found significantly increased odds of MCI in those reporting high blood pressure (OR = 5.27; 95% CI: [1.36, 20.46]; p = 0.016), high cholesterol (OR = 7.30; 95% CI: [1.90, 28.14], p = 0.004), and prediabetes or borderline diabetes (OR = 4.53; 95% CI: [1.27, 16.16], p = 0.02) compared with those not reporting these respective conditions. These data show that hypertension, hypercholesterolemia, and prediabetes are associated with MCI in the NHPI community, suggesting that preventive strategies to reduce chronic conditions may also potentially slow cognitive decline in underrepresented/understudied NHPI.

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夏威夷原住民和太平洋岛民的合并症与认知障碍有关。

我们研究了夏威夷原住民和太平洋岛民（NHPI）（n = 54）的合并症与轻度认知障碍（MCI）之间的关系。我们利用横断面自我报告问卷收集了人口统计学、合并症和 MCI（通过 AD8 指数）数据。在对其他协变量进行调整后，我们分别建立了逻辑回归模型来研究合并症与 MCI 之间的关系。我们发现，与未报告高血压（OR = 5.27；95% CI：[1.36, 20.46]；P = 0.016）、高胆固醇（OR = 7.30；95% CI：[1.90, 28.14]；P = 0.004）、糖尿病前期或边缘糖尿病（OR = 4.53；95% CI：[1.27, 16.16]；P = 0.02）的患者相比，报告这些疾病的患者发生 MCI 的几率明显增加。这些数据表明，高血压、高胆固醇血症和糖尿病前期与非裔美国人社区中的 MCI 相关，这表明减少慢性疾病的预防策略也可能减缓代表性不足/研究不足的非裔美国人的认知能力下降。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Aging & Human Development Multiple-

CiteScore

4.10

自引率

5.00%

发文量

期刊介绍： These are some of the broad questions with which the International Journal of Aging and Human Development is concerned. Emphasis is upon psychological and social studies of aging and the aged. However, the Journal also publishes research that introduces observations from other fields that illuminate the "human" side of gerontology, or utilizes gerontological observations to illuminate in other fields.