Prevalence of delayed initiation of rabies postexposure prophylaxis and factors influencing it among animal bite victims from Eastern Uttar Pradesh, India.

IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Imran Ahmed Khan, M D Abu Bashar, Sufiya Mohsin, D K Shrivastava
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引用次数: 0

Abstract

Background: In a rabies-endemic country like India, every animal bite is potentially taken as rabid exposure and timely and appropriate postexposure prophylaxis (PEP) is crucial as rabies is an almost 100% fatal disease.

Methods: A retrospective record-based study was conducted at an anti-rabies clinic (ARC) in Eastern Uttar Pradesh, India. Data of the animal bite victims attending the ARC for PEP from January to December 2022 were extracted from the records. A semistructured questionnaire was used for collecting information regarding the interval between exposure and the initiation of anti-rabies PEP, age, gender, residence, the bite site on the body, category of exposure and other risk factors associated with the delay in PEP.

Results: Most of the victims were male (67.6%), from an urban background (61.3%) and aged up to 20 y (43.9%). Out of the 222 victims, 62 (27.9%) had delayed initiation of PEP (>48 h after exposure). Factors found to be significantly associated with delayed initiation of PEP were residence (p=0.01), age (p=0.04) and the type of biting animal (p=0.002).

Conclusions: Delayed initiation of PEP is common among animal bite victims in this region of India, although PEP is affordable. Educational programmes and awareness-raising campaigns for timely administration of PEP should be a priority, especially targeting rural residents, those aged<18 y and those bitten by animals other than dogs.

印度北方邦东部被动物咬伤者中狂犬病暴露后预防措施延迟启动的普遍性及其影响因素。
背景:在印度这样一个狂犬病流行的国家,每一次被动物咬伤都有可能被视为狂犬病暴露,及时、适当的暴露后预防(PEP)至关重要,因为狂犬病几乎是一种100%致命的疾病:在印度北方邦东部的一家抗狂犬病诊所(ARC)开展了一项基于记录的回顾性研究。研究人员从记录中提取了 2022 年 1 月至 12 月在 ARC 接受预防性治疗的动物咬伤患者的数据。研究采用半结构化问卷调查的方式,收集了从接触动物到开始接受抗狂犬病PEP治疗之间的间隔时间、年龄、性别、居住地、身体被咬伤的部位、接触动物的类别以及与延迟接受PEP治疗相关的其他风险因素等信息:大多数受害者为男性(67.6%),来自城市(61.3%),年龄在20岁以下(43.9%)。在 222 名受害者中,有 62 人(27.9%)延迟开始进行预防性保护(暴露后超过 48 小时)。研究发现,居住地(P=0.01)、年龄(P=0.04)和咬人动物的类型(P=0.002)与延迟启动PEP有明显关系:结论:在印度的这个地区,尽管动物咬伤患者能够负担得起 PEP 的费用,但延迟启动 PEP 的情况在动物咬伤患者中很常见。应优先考虑及时实施 PEP 的教育计划和提高认识运动,特别是针对农村居民、年龄在 65 岁以上的人和儿童。
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来源期刊
Transactions of The Royal Society of Tropical Medicine and Hygiene
Transactions of The Royal Society of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生
CiteScore
4.00
自引率
9.10%
发文量
115
审稿时长
4-8 weeks
期刊介绍: Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.
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