Psychosocial Burden in People with Atopic Dermatitis: Effects of a Substance-Free Basic Skincare in a Randomized Health Care Study.

IF 2.8 4区医学 Q2 DERMATOLOGY

Skin Pharmacology and Physiology Pub Date : 2023-01-01 Epub Date: 2024-02-07 DOI:10.1159/000536671

Catharina Braren-von Stülpnagel, Matthias Augustin, Rachel Sommer, Lukas Westphal

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引用次数: 0

Abstract

Introduction: Atopic dermatitis (AD) is a physical, emotional, and social burden for patients. Most suffer from itching, pain, and dry skin as well as sleep disturbances, experienced stigmatization, anxiety, or depression. Therefore, it is important to consider the psychosocial well-being and also stigmatization in the treatment of people with AD. The aims of this study were to compare clinical and psychosocial parameters between patients with a different severity of AD and to analyse the effect of an omega-6-fatty-acid-skin therapy.

Methods: Adult patients with clinically confirmed AD were asked about quality of life, stigmatization, and well-being after dermatological diagnosis. A second examination took place after 2-5 weeks. Meanwhile, after randomization, half of the patients used an omega-6-fatty-acid-skin therapy.

Results: Seventy-nine patients were included in the study. The use of omega-6-fatty-acid-skin therapy resulted in a significant reduction in the severity of xerosis cutis compared to patients using another basic therapy. In addition, the health-related quality of life of all patients improved significantly in both groups (F = 7.56; p = 0.008), and no significant difference was found between the groups over time in the patient-reported outcomes.

Conclusion: Basic therapy for AD leads to relevant improvements in clinical status as well as quality of life. Patients using omega-6-fatty-acid-skin therapy experience greater improvement in xerosis cutis compared to free-choice basic therapy.

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特应性皮炎患者的社会心理负担--随机医疗保健研究中的无物质基础皮肤护理效果。

背景：特应性皮炎（AD）给患者带来身体、精神和社会负担。大多数患者都有皮肤瘙痒、疼痛、干燥、睡眠障碍、耻辱感、焦虑或抑郁等问题。因此，在治疗 AD 患者的过程中，考虑社会心理健康和耻辱感非常重要：本研究旨在比较不同严重程度的注意力缺失症患者的临床和社会心理参数，并分析奥米加-6脂肪酸皮肤疗法的效果：对经临床确诊的注意力缺失症成年患者进行皮肤病诊断后的生活质量、耻辱感和幸福感调查。2至5周后进行第二次检查。同时，在随机分配后，半数患者使用了欧米茄-6脂肪酸皮肤疗法：79名患者参与了研究。与使用其他基本疗法的患者相比，使用欧米伽-6脂肪酸皮肤疗法可显著减轻皮肤干燥症的严重程度。此外，两组所有患者的健康相关生活质量均有明显改善（F = 7.56; p = 0.008），但在患者报告的结果方面，两组之间没有发现明显的时间差异：结论：AD的基础治疗可明显改善患者的临床状况和生活质量。结论：与自由选择的基础疗法相比，使用欧米伽-6脂肪酸皮肤疗法的患者皮肤角化症的改善程度更大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Skin Pharmacology and Physiology 医学-皮肤病学

CiteScore

5.20

自引率

7.40%

发文量

审稿时长

>12 weeks

期刊介绍： In the past decade research into skin pharmacology has rapidly developed with new and promising drugs and therapeutic concepts being introduced regularly. Recently, the use of nanoparticles for drug delivery in dermatology and cosmetology has become a topic of intensive research, yielding remarkable and in part surprising results. Another topic of current research is the use of tissue tolerable plasma in wound treatment. Stimulating not only wound healing processes but also the penetration of topically applied substances into the skin, this novel technique is expected to deliver very interesting results.