Effects of water quality on palladium-induced olfactory toxicity and bioaccumulation in rainbow trout (Oncorhynchus mykiss)

IF 3 4区环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES

Integrated Environmental Assessment and Management Pub Date : 2024-02-08 DOI:10.1002/ieam.4900

Carolyn Simonis, Lauren Zink, Sarah E. Johnston, Matthew Bogard, Gregory G. Pyle

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Abstract

Through emission processes, palladium (Pd) particulates from industrial sources are introduced into a range of ecosystems including freshwater environments. Despite this, research on Pd-induced bioaccumulation, uptake, and toxicity is limited for freshwater fishes. Unlike other metals, there are currently no regulations or protective guidelines to limit Pd release into aquatic systems, indicating a global absence of measures addressing its environmental impact. To assess the olfactory toxicity potential of Pd, the present study aimed to explore Pd accumulation in olfactory tissues, olfactory disruption, and oxidative stress in rainbow trout (Oncorhynchus mykiss) following waterborne Pd exposure. Olfactory sensitivity, measured by electro-olfactography, demonstrated that Pd inhibits multiple pathways of the olfactory system following 96 h of Pd exposure. In this study, the concentrations of Pd for inhibition of olfactory function by 20% (2.5 μg/L; IC20) and 50% (19 μg/L; IC50) were established. Rainbow trout were then exposed to IC20 and IC50 Pd concentrations in combination with varying exposure conditions, as changes in water quality alter the toxicity of metals. Independent to Pd, increased water hardness resulted in decreased olfactory perception owing to ion competition at the olfactory epithelium. No other environmental parameter in this study significantly influenced Pd-induced olfactory toxicity. Membrane-associated Pd was measured at the olfactory rosette and gill following exposure; however, this accumulation did not translate to oxidative stress as measured by the production of malondialdehyde. Our data suggest that Pd is toxic to rainbow trout via waterborne contamination near field-measured levels. This study further demonstrated Pd bioavailability and uptake at water-adjacent tissues, adding to our collective understanding of the toxicological profile of Pd. Taken together, our results provide novel insights into the olfactory toxicity in fish following Pd exposure. Integr Environ Assess Manag 2024;20:1407–1419. © 2024 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).

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水质对虹鳟鱼（Oncorhynchus mykiss）嗅觉毒性和生物累积的影响。

通过排放过程，工业来源的钯（Pd）微粒被引入包括淡水环境在内的一系列生态系统。尽管如此，有关淡水鱼类对钯的生物累积、吸收和毒性的研究仍然有限。与其他金属不同，目前还没有限制钯释放到水生系统中的法规或保护指南，这表明全球缺乏应对钯对环境影响的措施。为了评估钯的嗅觉毒性潜力，本研究旨在探讨虹鳟鱼（Oncorhynchus mykiss）接触水传播的钯后，嗅觉组织中钯的积累、嗅觉干扰和氧化应激。通过电-olfactography 测量的嗅觉灵敏度表明，接触钯 96 小时后，钯会抑制嗅觉系统的多种途径。本研究确定了抑制嗅觉功能 20%（2.5 μg/L；IC20）和 50%（19 μg/L；IC50）的钯浓度。由于水质的变化会改变金属的毒性，因此将虹鳟鱼暴露在 IC20 和 IC50 Pd 浓度以及不同的暴露条件下。与钯无关，由于嗅觉上皮的离子竞争，水硬度增加会导致嗅觉感知能力下降。在本研究中，没有其他环境参数对钯诱导的嗅觉毒性产生显著影响。接触钯后，在嗅莲座和鳃部测量到了膜结合钯；然而，通过丙二醛的产生来测量，这种积累并没有转化为氧化应激。我们的数据表明，钯通过水源污染对虹鳟具有毒性，接近现场测量的水平。这项研究进一步证明了钯的生物利用率以及水体邻近组织对钯的吸收，从而加深了我们对钯毒理学特征的理解。总之，我们的研究结果为了解鱼类接触钯后的嗅觉毒性提供了新的视角。Integr Environ Assess Manag 2024;00:1-13。© 2024 作者。综合环境评估与管理》由 Wiley Periodicals LLC 代表环境毒理学与化学学会 (SETAC) 出版。

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来源期刊

Integrated Environmental Assessment and Management ENVIRONMENTAL SCIENCESTOXICOLOGY&nbs-TOXICOLOGY

CiteScore

5.90

自引率

6.50%

发文量

156

期刊介绍： Integrated Environmental Assessment and Management (IEAM) publishes the science underpinning environmental decision making and problem solving. Papers submitted to IEAM must link science and technical innovations to vexing regional or global environmental issues in one or more of the following core areas: Science-informed regulation, policy, and decision making Health and ecological risk and impact assessment Restoration and management of damaged ecosystems Sustaining ecosystems Managing large-scale environmental change Papers published in these broad fields of study are connected by an array of interdisciplinary engineering, management, and scientific themes, which collectively reflect the interconnectedness of the scientific, social, and environmental challenges facing our modern global society: Methods for environmental quality assessment; forecasting across a number of ecosystem uses and challenges (systems-based, cost-benefit, ecosystem services, etc.); measuring or predicting ecosystem change and adaptation Approaches that connect policy and management tools; harmonize national and international environmental regulation; merge human well-being with ecological management; develop and sustain the function of ecosystems; conceptualize, model and apply concepts of spatial and regional sustainability Assessment and management frameworks that incorporate conservation, life cycle, restoration, and sustainability; considerations for climate-induced adaptation, change and consequences, and vulnerability Environmental management applications using risk-based approaches; considerations for protecting and fostering biodiversity, as well as enhancement or protection of ecosystem services and resiliency.