Role of Nanoformulations in the Treatment of Lung Cancer.

IF 2 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY
Parijat Pandey, Gunjan Nautiyal, Deepika Purohit, Sneh Lata, Virender Kumar, Manish Makhija, Deeksha Manchanda, Neha Minocha, Sunil Kumar, Deepak Kaushik
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引用次数: 0

Abstract

Lung cancer is the second deadliest disease in the world. A major portion of deaths related to cancer are due to lung cancer in both males and females. Interestingly, unbelievable advances have occurred in recent years through the use of nanotechnology and development in both the diagnosis and treatment of lung cancer. Due to their in vivo stability, the nanotechnology-based pharmacological system gained huge attractiveness, solubility, absorption from the intestine, pharmacological effectiveness, etc. of various anticancer agents. However, this field needs to be utilized more to get maximum results in the treatment of lung cancer, along with wider context medicines. In the present review, authors have tried to concentrate their attention on lung cancer`s difficulties along with the current pharmacological and diagnostic situation, and current advancements in approaches based on nanotechnology for the treatment and diagnosis of lung cancer. While nanotechnology offers these promising avenues for lung cancer diagnosis and treatment, it is important to acknowledge the need for careful evaluation of safety, efficacy, and regulatory approval. With continued research and development, nanotechnology holds tremendous potential to revolutionize the management of lung cancer and improve patient outcomes. The review also highlights the involvement of endocrine systems, especially estrogen in lung cancer proliferation. Some of the recent clinical trials and patents on nanoparticle-based formulations that have applications in the treatment and diagnosis of lung cancer are also discussed.

纳米制剂在肺癌治疗中的作用。
肺癌是世界上第二致命的疾病。在与癌症相关的死亡病例中,大部分男性和女性都死于肺癌。有趣的是,近年来通过纳米技术的使用和发展,肺癌的诊断和治疗都取得了令人难以置信的进展。由于其体内稳定性,基于纳米技术的药理系统在各种抗癌剂的溶解性、肠道吸收、药理有效性等方面获得了巨大的吸引力。然而,要想在肺癌治疗中取得最大效果,还需要更多地利用这一领域以及更广泛的药物。在本综述中,作者试图集中关注肺癌的难点、当前的药理和诊断情况,以及基于纳米技术的肺癌治疗和诊断方法的最新进展。虽然纳米技术为肺癌诊断和治疗提供了前景广阔的途径,但必须认识到需要对安全性、有效性和监管审批进行仔细评估。随着研究和开发的不断深入,纳米技术具有巨大的潜力,可以彻底改变肺癌的治疗方法并改善患者的预后。综述还强调了内分泌系统,尤其是雌激素参与肺癌增殖的情况。此外,还讨论了最近一些应用于肺癌治疗和诊断的纳米颗粒制剂的临床试验和专利。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Recent Patents on Nanotechnology
Recent Patents on Nanotechnology NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY
CiteScore
4.70
自引率
10.00%
发文量
50
审稿时长
3 months
期刊介绍: Recent Patents on Nanotechnology publishes full-length/mini reviews and research articles that reflect or deal with studies in relation to a patent, application of reported patents in a study, discussion of comparison of results regarding application of a given patent, etc., and also guest edited thematic issues on recent patents in the field of nanotechnology. A selection of important and recent patents on nanotechnology is also included in the journal. The journal is essential reading for all researchers involved in nanotechnology.
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