Pain medication misuse in the South African spinal cord injury context.

IF 1.1 Q4 HEALTH CARE SCIENCES & SERVICES
Health SA Gesondheid Pub Date : 2024-01-31 eCollection Date: 2024-01-01 DOI:10.4102/hsag.v29i0.2377
Mokgadi K Mashola, Elzette Korkie, Diphale J Mothabeng
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引用次数: 0

Abstract

Background: Pain after spinal cord injury (SCI) is debilitating and has been reported to be difficult to treat, despite pharmacological interventions. Pain medication misuse (PMM) and associated individual factors among people with spinal cord injury (PWSCI) are scarce.

Aim: To determine PMM and the associated factors in PWSCI.

Setting: Homes of community-dwelling manual wheelchair users with SCI in South Africa.

Methods: Community-dwelling PWSCI (n = 122) were consecutively sampled and the Pain Medication Questionnaire (PMQ) was used to determine PMM. Descriptive statistics, Fisher's exact test, independent t-tests, and simple linear regression tests were performed using SPSS v27. Testing was conducted at the 0.05 level of significance.

Results: Eighty-five per cent of the participants reported the presence of pain and 48.1% of them used pain medication. Forty-four percent of people who used pain medication scored ≥ 30, indicative of serious aberrant drug-taking behaviours. Opioids were mainly used for neuropathic pain and in combination with other types of medications such as anticonvulsants and non-steroidal anti-inflammatories (44.0%). Pain severity and the type of pain medication were found to be predictors of PMM (p < 0.01 respectively).

Conclusion: Pain relief after SCI remains difficult to achieve, with an evident high risk of PMM, which may lead to long-lasting side effects, dependency, or overdose.

Contribution: This study has shown the need for the assessment of the potential risk of dependency before prescribing pain medication, particularly opioids to PWSCI.

南非脊髓损伤患者滥用止痛药的情况。
背景:脊髓损伤(SCI)后的疼痛使人衰弱,尽管有药物干预,但据报道很难治疗。脊髓损伤患者(PWSCI)中滥用止痛药物(PMM)及相关个人因素的情况很少见:环境:南非社区手动轮椅脊髓损伤患者的家庭:连续抽样调查了居住在社区的PWSCI(n = 122),并使用疼痛用药问卷(PMQ)来确定PMM。使用 SPSS v27 进行了描述性统计、费雪精确检验、独立 t 检验和简单线性回归检验。检验的显著性水平为 0.05:85%的参与者表示有疼痛感,其中 48.1%的人使用过止痛药。在使用止痛药物的人中,44%的人得分≥30,表明有严重的异常服药行为。阿片类药物主要用于神经性疼痛,并与抗惊厥药和非甾体抗炎药等其他类型的药物联合使用(44.0%)。研究发现,疼痛严重程度和止痛药物类型是 PMM 的预测因素(P 分别小于 0.01):结论:脊髓损伤后的疼痛缓解仍然难以实现,PMM的风险显然很高,可能导致长期副作用、依赖性或用药过量:本研究表明,在为 SCI 患者开具止痛药(尤其是阿片类药物)处方之前,有必要对潜在的依赖性风险进行评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Health SA Gesondheid
Health SA Gesondheid HEALTH CARE SCIENCES & SERVICES-
CiteScore
1.40
自引率
11.10%
发文量
77
审稿时长
23 weeks
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