Association and Interacting Factors between Bronchial Asthma and Attention-deficit Hyperactivity Disorder in Children: Meta-analysis and Systematic Review.

IF 1 4区 医学 Q4 NEUROSCIENCES
Actas espanolas de psiquiatria Pub Date : 2023-12-01
Yongjun Dai, Ni Jin
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引用次数: 0

Abstract

Background: This study aims to systematically assess the possible link between bronchial asthma usage and attention-deficit hyperactivity disorder (ADHD) in children.

Methods: PubMed, Web of Science, ScienceDirect, CNKI, Wanfang, and the China Biological Medicine Database (CBM) were searched for relevant articles published from database inception until September 28, 2023. The statistical analyses were conducted using Stata 15.1 software, followed by a quantitative meta-analysis to synthesize the results of the odds ratios (ORs) and their corresponding 95% confidence intervals (CIs).

Results: A total of 10 articles involving 729,375 participants were included in the meta-analysis. The overall analysis revealed a statistically significant association between ADHD and an increased likelihood of having bronchial asthma, as indicated by a pooled odds ratio (OR) of 1.46 and a 95% confidence interval (CI) ranging from 1.41 to 1.51, p < 0.001, I2 = 58%. Potential associated factors linking bronchial asthma and ADHD in children include demographic characteristics, healthcare access, socioeconomic factors, comorbidities, genetic susceptibility, immune dysregulation, chronic conditions, growth and development factors, and parental/environmental influences.

Conclusion: This systematic review and meta-analysis presents convincing evidence for a notable link between bronchial asthma and ADHD in children. The results indicate an increased likelihood of bronchial asthma among children with ADHD compared to those without the condition. Additionally, various potential factors can underlie the association between bronchial asthma and ADHD in children, necessitating further research to fully comprehend their complex relationship. These findings have implications for clinical practice, highlighting the need for an integrated approach in managing asthma and ADHD.

儿童支气管哮喘与注意力缺陷多动障碍之间的关联和相互作用因素:元分析和系统综述》(Meta-analysis and Systematic Review)。
背景:本研究旨在系统评估支气管哮喘与儿童注意力缺陷多动症(ADHD)之间可能存在的联系:本研究旨在系统评估支气管哮喘的使用与儿童注意缺陷多动障碍(ADHD)之间可能存在的联系:方法:检索PubMed、Web of Science、ScienceDirect、CNKI、万方数据库和中国生物医学数据库(CBM)中自数据库建立至2023年9月28日发表的相关文章。使用Stata 15.1软件进行统计分析,然后进行定量荟萃分析,综合得出几率比(ORs)及其相应的95%置信区间(CIs)的结果:荟萃分析共纳入了 10 篇文章,涉及 729 375 名参与者。总体分析结果显示,多动症与支气管哮喘患病几率增加之间存在统计学意义上的显著关联,汇总几率比(OR)为1.46,95%置信区间(CI)为1.41-1.51,P < 0.001,I2 = 58%。将儿童支气管哮喘与多动症联系在一起的潜在相关因素包括人口统计学特征、医疗保健途径、社会经济因素、合并症、遗传易感性、免疫失调、慢性疾病、生长发育因素以及父母/环境影响:本系统综述和荟萃分析提供了令人信服的证据,证明支气管哮喘与儿童多动症之间存在显著联系。研究结果表明,与非多动症儿童相比,多动症儿童患支气管哮喘的可能性更大。此外,支气管哮喘与儿童多动症之间的联系可能存在各种潜在因素,因此有必要开展进一步研究,以全面了解两者之间的复杂关系。这些研究结果对临床实践具有启示意义,强调了采用综合方法管理哮喘和多动症的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Actas espanolas de psiquiatria
Actas espanolas de psiquiatria 医学-精神病学
CiteScore
1.70
自引率
6.70%
发文量
46
审稿时长
>12 weeks
期刊介绍: Actas Españolas de Psiquiatría publicará de manera preferente trabajos relacionados con investigación clínica en el área de la Psiquiatría, la Psicología Clínica y la Salud Mental.
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