{"title":"Cereal-derived polyphenols and their bioactive properties","authors":"Si Nhat Nguyen, Trust Beta","doi":"10.1016/j.cofs.2024.101136","DOIUrl":null,"url":null,"abstract":"<div><p>Cereal grains can be considered as a package containing different nutritional and nutraceutical components. Their polyphenolic compounds are associated with health-promoting bioactivities. Recent investigations are directed toward achieving a greener extraction of polyphenols, discovery of new bioactive polyphenols, coupled with rapid determination of phenolics and their antioxidant capacity in cereal grains. Phenolamides, conjugates between phenolic acids and biogenic amines, have recently been reported in minor cereal crops. Mechanisms underlying the systemic health-promoting properties of polyphenolic substances from cereals include antioxidant, anti-inflammatory, antidiabetic, and antiobesity properties. Both cellular and <em>in vivo</em> approaches are being employed to better reflect the biological relevance. However, the therapeutic agents examined to date have been limited to pure compounds and extractable polyphenols. The systemic health-promoting properties of cereal-derived polyphenols play a pivotal role in the delivery of their localized protective impacts on various tissues in different parts of the human body. The application of network pharmacology has enabled the exploration of new bioactivities of cereal-derived polyphenols. Metabolomic approaches have been employed to gain understanding of the bioaccessibility and bioavailability of diverse phenolic compounds from different cereal-based matrices. The polyphenols that are covalently linked to cell wall components of cereal grains are likely to escape the digestion but still contribute to the maintenance and enhancement of human health status.</p></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":null,"pages":null},"PeriodicalIF":8.9000,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214799324000146/pdfft?md5=0de740ebdfed4be5214eb366dddb2e31&pid=1-s2.0-S2214799324000146-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Food Science","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214799324000146","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Cereal grains can be considered as a package containing different nutritional and nutraceutical components. Their polyphenolic compounds are associated with health-promoting bioactivities. Recent investigations are directed toward achieving a greener extraction of polyphenols, discovery of new bioactive polyphenols, coupled with rapid determination of phenolics and their antioxidant capacity in cereal grains. Phenolamides, conjugates between phenolic acids and biogenic amines, have recently been reported in minor cereal crops. Mechanisms underlying the systemic health-promoting properties of polyphenolic substances from cereals include antioxidant, anti-inflammatory, antidiabetic, and antiobesity properties. Both cellular and in vivo approaches are being employed to better reflect the biological relevance. However, the therapeutic agents examined to date have been limited to pure compounds and extractable polyphenols. The systemic health-promoting properties of cereal-derived polyphenols play a pivotal role in the delivery of their localized protective impacts on various tissues in different parts of the human body. The application of network pharmacology has enabled the exploration of new bioactivities of cereal-derived polyphenols. Metabolomic approaches have been employed to gain understanding of the bioaccessibility and bioavailability of diverse phenolic compounds from different cereal-based matrices. The polyphenols that are covalently linked to cell wall components of cereal grains are likely to escape the digestion but still contribute to the maintenance and enhancement of human health status.
期刊介绍:
Current Opinion in Food Science specifically provides expert views on current advances in food science in a clear and readable format. It also evaluates the most noteworthy papers from original publications, annotated by experts.
Key Features:
Expert Views on Current Advances: Clear and readable insights from experts in the field regarding current advances in food science.
Evaluation of Noteworthy Papers: Annotated evaluations of the most interesting papers from the extensive array of original publications.
Themed Sections: The subject of food science is divided into themed sections, each reviewed once a year.