Micronutrient Research in Autism Spectrum Disorder. A Clinical Study.

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI:10.12865/CHSJ.49.03.14
Cătălina Mihaela Anastasescu, Eugen Stoicănescu, Oana Badea, Florica Popescu
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Abstract

Autistic spectrum disorders are part of the category of neurodevelopmental disorders, characterized by: difficulties in communication and social interaction, restrictive and repetitive patterns of behaviours and activities, which are present throughout the developmental period, and can be diagnosed in the first five years of life. Due to the increase in the incidence of this disorder in recent years, it has become a topic of great interest both to specialists in child and adolescent psychiatry and to researchers in the field. Given the polymorphism of Autism Spectrum Disorder and the need to discover factors that better explain the etiology of this disorder, studies related to biomarkers are extremely varied. One of the areas of study that have exercised particular interest is related to the involvement of metals in the pathology of autism spectrum disorder. Apart from the controversies related to heavy metals that according to studies affect the developmental process, there are studies that suggest that some micronutrients such as zinc, copper, selenium, iron, magnesium, may be involved in the etiology of autism spectrum disorder. Starting from these studies, we set out to investigate to what extent these essential metals for the body are involved in the etiology of autism spectrum disorder and how they influence the severity of symptoms.

自闭症谱系障碍中的微量营养素研究。临床研究。
自闭症谱系障碍(Autistic spectrum disorders)是神经发育障碍的一种,其特点是:沟通和社会交往困难,行为和活动模式具有限制性和重复性,在整个发育阶段都存在,可在出生后的头五年被诊断出来。由于近年来自闭症发病率的上升,它已成为儿童和青少年精神病学专家以及该领域研究人员极为关注的话题。鉴于自闭症谱系障碍的多态性,以及发现能更好地解释这种障碍病因的因素的必要性,与生物标志物有关的研究极为多样。自闭症谱系障碍病理学中的金属参与是其中一个引起特别关注的研究领域。除了与重金属有关的争议(根据研究,重金属会影响发育过程),还有研究表明,一些微量元素,如锌、铜、硒、铁、镁,可能与自闭症谱系障碍的病因有关。从这些研究出发,我们着手调查这些人体必需的金属元素在多大程度上参与了自闭症谱系障碍的病因学研究,以及它们如何影响症状的严重程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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