Demystifying vascularized lymph node transfers and lymphatico-venous anastomoses.

4区 医学
Annals of translational medicine Pub Date : 2024-02-01 Epub Date: 2023-07-10 DOI:10.21037/atm-23-132
Yasser Almadani, Peter Davison, Johnny Ionut Efanov, George Kokosis, Joshua Vorstenbosch
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引用次数: 0

Abstract

Lymphedema continues to be a widely prevalent condition with no definitive cure. It affects a wide range of patients across different ages and backgrounds. The significant burden of this chronic and debilitating condition necessitates more research and comprehensive healthcare coverage for affected patients. In developed countries, cancer survivors are disproportionality affected by this condition. Risk factors including lymph node dissections and radiation render many cancer patients more susceptible to the development of lymphedema. Part of the challenge with lymphedema care, is that it exits on a broad spectrum with significant variability of symptoms. Advances and broader availability of various imaging modalities continue to foster progress in lymphedema surgery. The conservative management of lymphedema remains the primary initial management option. However, lymphedema surgeries can provide significant hope and may pave the way for significant improvements in the quality-of-life for many patients afflicted by this progressive and enfeebling condition. Reductive and physiologic procedures are becoming an important part of the armamentarium of the modern plastic and reconstructive surgeon. Recent advances in physiologic lymphedema surgeries are accelerating their transition from experimental surgeries to broadly adopted and widely accepted procedures that can lead to major successes in the fight against this condition. Prophylactic lymphedema surgery also presents a promising choice for many patients and can help prevent lymphedema development in high-risk patients.

揭开血管淋巴结转移和淋巴-静脉吻合的神秘面纱。
淋巴水肿仍然是一种广泛流行的疾病,目前尚无确切的治疗方法。它影响着不同年龄和背景的各类患者。这种使人衰弱的慢性疾病造成了沉重的负担,因此有必要开展更多的研究,并为受影响的患者提供全面的医疗保健服务。在发达国家,癌症幸存者受这种疾病的影响不成比例。包括淋巴结切除和辐射在内的风险因素使许多癌症患者更容易患上淋巴水肿。淋巴水肿护理所面临的部分挑战是,淋巴水肿的范围很广,症状变化很大。各种成像模式的进步和普及不断推动着淋巴水肿手术的发展。淋巴水肿的保守治疗仍然是最初的主要治疗方案。然而,淋巴水肿手术可以给患者带来巨大的希望,并为显著改善许多患者的生活质量铺平道路。减少性和生理性淋巴水肿手术正在成为现代整形外科医生的重要手段之一。生理性淋巴水肿手术的最新进展正加速其从实验性手术向广泛采用和普遍接受的手术过渡,从而在与淋巴水肿的斗争中取得重大胜利。对于许多患者来说,预防性淋巴水肿手术也是一种很有前景的选择,它可以帮助高危患者预防淋巴水肿的发生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
自引率
0.00%
发文量
769
期刊介绍: The Annals of Translational Medicine (Ann Transl Med; ATM; Print ISSN 2305-5839; Online ISSN 2305-5847) is an international, peer-reviewed Open Access journal featuring original and observational investigations in the broad fields of laboratory, clinical, and public health research, aiming to provide practical up-to-date information in significant research from all subspecialties of medicine and to broaden the readers’ vision and horizon from bench to bed and bed to bench. It is published quarterly (April 2013- Dec. 2013), monthly (Jan. 2014 - Feb. 2015), biweekly (March 2015-) and openly distributed worldwide. Annals of Translational Medicine is indexed in PubMed in Sept 2014 and in SCIE in 2018. Specific areas of interest include, but not limited to, multimodality therapy, epidemiology, biomarkers, imaging, biology, pathology, and technical advances related to medicine. Submissions describing preclinical research with potential for application to human disease, and studies describing research obtained from preliminary human experimentation with potential to further the understanding of biological mechanism underlying disease are encouraged. Also warmly welcome are studies describing public health research pertinent to clinic, disease diagnosis and prevention, or healthcare policy.
 With a focus on interdisciplinary academic cooperation, ATM aims to expedite the translation of scientific discovery into new or improved standards of management and health outcomes practice.
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