α-Boryl Carbanions: The Influence of Geminal Heteroatoms in C−C Bond Formation

IF 7 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Chemical record Pub Date : 2024-02-02 DOI:10.1002/tcr.202300349

Prof. Elena Fernández

引用次数: 0

Abstract

The wide applications of alpha-boryl carbanions in selective coupling with organohalides, imines/carbonyls and conjugated unsaturated substrates has become an interesting tool for organic synthesis. Strategically, the inclusion of heteroatoms, such as Si, S, N, F, Cl, Br and I in the alpha position opens a new venue towards multifunctionalities in molecular design. Here, a conceptual and practical view on powerful carbanions, containing α-silicoboron, α-thioboron, α-haloboron and α-aminoboron is given, as well as a prespective on their efficient application for selective electrophilic trapping.

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α-Boryl Carbanions：宝石杂原子对 C-C 键形成的影响。

在与有机卤化物、亚胺/羰基化合物和共轭不饱和底物的选择性偶联中，α-硼烷碳离子的广泛应用已成为有机合成的一种有趣工具。从战略上讲，在α位加入杂原子（如Si、S、N、F、Cl、Br和I）为分子设计的多功能性开辟了新的途径。在此，我们将从概念和实践的角度介绍含有 α-硅硼、α-硫硼、α-卤硼和α-氨基硼的强力碳离子，并展望它们在选择性亲电捕获中的有效应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical record 化学-化学综合

CiteScore

11.00

自引率

3.00%

发文量

188

审稿时长

>12 weeks

期刊介绍： The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields. TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.