David Fonseca Hernandez , Luis Mojica , Elvira Gonzalez de Mejia
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引用次数: 0
Abstract
Cardiovascular diseases (CVDs) are a health problem worldwide. The use of peptides and protein hydrolysates derived from legumes to prevent and treat them has increased in recent years. In vitro and in vivo data support the efficacy of peptide interaction with markers associated with hypertension, endothelium dysfunction, and atherosclerosis. However, challenges such as misunderstanding their mechanism of action, safety, bioavailability, bitter taste, and cost-effective production limit their clinical and commercial translation. We analyzed and summarized recent findings related to legume-derived peptides and their mechanism of action associated with CVDs, including novel target markers associated with lipid metabolism, such as the inflammasome, angiopoietin-like protein 3, and proprotein convertase subtilisin/kexin 9.
期刊介绍:
Current Opinion in Food Science specifically provides expert views on current advances in food science in a clear and readable format. It also evaluates the most noteworthy papers from original publications, annotated by experts.
Key Features:
Expert Views on Current Advances: Clear and readable insights from experts in the field regarding current advances in food science.
Evaluation of Noteworthy Papers: Annotated evaluations of the most interesting papers from the extensive array of original publications.
Themed Sections: The subject of food science is divided into themed sections, each reviewed once a year.