A 2.3–5.7 μW Tri-Modal Self-Adaptive Photoplethysmography Sensor Interface IC for Heart Rate, SpO2, and Pulse Transit Time Co-Monitoring

Peng Wang;Rishika Agarwala;Natalie B. Ownby;Xinjian Liu;Benton H. Calhoun
{"title":"A 2.3–5.7 μW Tri-Modal Self-Adaptive Photoplethysmography Sensor Interface IC for Heart Rate, SpO2, and Pulse Transit Time Co-Monitoring","authors":"Peng Wang;Rishika Agarwala;Natalie B. Ownby;Xinjian Liu;Benton H. Calhoun","doi":"10.1109/TBCAS.2024.3360140","DOIUrl":null,"url":null,"abstract":"This paper presents a tri-modal self-adaptive photoplethysmography (PPG) sensor interface IC for concurrently monitoring heart rate, SpO\n<sub>2</sub>\n, and pulse transit time, which is a critical intermediate parameter to derive blood pressure. By implementing a highly-reconfigurable analog front-end (AFE) architecture, flexible signal chain timing control, and flexible dual-LED drivers, this sensor interface provides wide operating space to support various PPG-sensing use cases. A heart-beat-locked-loop (HBLL) scheme is further extended to achieve time-multiplexed dual-input pulse transit time extraction based on two PPG sensors placed at fingertip and chest. A self-adaptive calibration scheme is proposed to automatically match the chip's operating point with the current use case, guaranteeing a sufficient signal-to-noise ratio for the user while consuming minimum system power. This paper proposes a DC offset cancellation (DCOC) approach comprised by a logarithmic transimpedance amplifier and an 8-bit SAR ADC, achieving a measured 38 nA residue error and 8.84 \n<italic>μ</i>\nA maximum input current. Fabricated in a 65nm CMOS process, the proposed tri-modal PPG sensor interface consumes 2.3–5.7 \n<italic>μ</i>\nW AFE power and 1.52 mm\n<sup>2</sup>\n die area with 102dB (SpO\n<sub>2</sub>\n mode), 110–116 dB (HR & PTT mode) dynamic range. A SpO\n<sub>2</sub>\n test case and a HR & PTT test case are both demonstrated in the paper, achieving 18.9 \n<italic>μ</i>\nW and 43.7 \n<italic>μ</i>\nW system power, respectively.","PeriodicalId":94031,"journal":{"name":"IEEE transactions on biomedical circuits and systems","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE transactions on biomedical circuits and systems","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/10416712/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

This paper presents a tri-modal self-adaptive photoplethysmography (PPG) sensor interface IC for concurrently monitoring heart rate, SpO 2 , and pulse transit time, which is a critical intermediate parameter to derive blood pressure. By implementing a highly-reconfigurable analog front-end (AFE) architecture, flexible signal chain timing control, and flexible dual-LED drivers, this sensor interface provides wide operating space to support various PPG-sensing use cases. A heart-beat-locked-loop (HBLL) scheme is further extended to achieve time-multiplexed dual-input pulse transit time extraction based on two PPG sensors placed at fingertip and chest. A self-adaptive calibration scheme is proposed to automatically match the chip's operating point with the current use case, guaranteeing a sufficient signal-to-noise ratio for the user while consuming minimum system power. This paper proposes a DC offset cancellation (DCOC) approach comprised by a logarithmic transimpedance amplifier and an 8-bit SAR ADC, achieving a measured 38 nA residue error and 8.84 μ A maximum input current. Fabricated in a 65nm CMOS process, the proposed tri-modal PPG sensor interface consumes 2.3–5.7 μ W AFE power and 1.52 mm 2 die area with 102dB (SpO 2 mode), 110–116 dB (HR & PTT mode) dynamic range. A SpO 2 test case and a HR & PTT test case are both demonstrated in the paper, achieving 18.9 μ W and 43.7 μ W system power, respectively.
用于心率、血氧饱和度和脉搏传输时间协同监测的 2.3-5.7μW 三模式自适应光敏传感器接口集成电路。
本文介绍了一种三模态自适应光心动图(PPG)传感器接口集成电路,用于同时监测心率、SpO2 和脉搏传输时间(推算血压的关键中间参数)。通过采用高度可配置的模拟前端(AFE)架构、灵活的信号链定时控制和灵活的双 LED 驱动器,该传感器接口为支持各种 PPG 传感用例提供了广阔的操作空间。心跳锁相环(HBLL)方案得到进一步扩展,以实现基于指尖和胸部两个 PPG 传感器的时间多路复用双输入脉冲传输时间提取。本文提出了一种自适应校准方案,可根据当前的使用情况自动匹配芯片的工作点,从而保证为用户提供足够的信噪比,同时将系统功耗降至最低。本文提出了一种由对数跨阻抗放大器和 8 位 SAR ADC 组成的直流偏移消除(DCOC)方法,实测残差误差为 38 nA,最大输入电流为 8.84 μA。拟议的三模 PPG 传感器接口采用 65nm CMOS 工艺制造,AFE 功耗为 2.3 - 5.7 μW,芯片面积为 1.52 mm2,动态范围为 102 dB(SpO2 模式)、110 - 116 dB(HR 和 PTT 模式)。文中演示了 SpO2 测试用例和 HR & PTT 测试用例,分别实现了 18.9 μW 和 43.7 μW 的系统功率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
文献相关原料
公司名称 产品信息 采购帮参考价格
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信