Metastatic neuroendocrine tumour of the orbit

Diagnostic Histopathology Pub Date : 2024-01-11 DOI:10.1016/j.mpdhp.2023.12.006

Harriet Hunter, Mike Thomas

引用次数: 0

Abstract

A 64-year-old patient presented with a tumour of the orbit. A biopsy showed an infiltrative tumour with coarse “salt-and-pepper” chromatin, showing strong expression of AE1/3, CD56, synaptophysin, chromogranin, and CDX2 on immunohistochemistry. The Ki67 proliferation index was low (<1%). The diagnosis of metastatic neuroendocrine tumour, most likely of gastrointestinal origin was favoured over a primary neuroendocrine tumour of the orbit.

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眼眶转移性神经内分泌肿瘤

一名 64 岁的患者因眼眶肿瘤就诊。活检显示肿瘤呈浸润性，染色质粗糙，免疫组化显示 AE1/3、CD56、突触素、嗜铬粒蛋白和 CDX2 表达较强。Ki67增殖指数较低（1%）。与眼眶原发性神经内分泌肿瘤相比，转移性神经内分泌肿瘤（很可能源于胃肠道）的诊断更受青睐。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic Histopathology Medicine-Pathology and Forensic Medicine

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.