Asociación entre periodontitis, enfermedad cerebrovascular y demencia. Informe científico del Grupo de Trabajo de la Sociedad Española de Periodoncia y la Sociedad Española de Neurología

IF 2.9 4区医学 Q2 CLINICAL NEUROLOGY

Neurologia Pub Date : 2024-01-13 DOI:10.1016/j.nrl.2023.11.003

Y. Leira , J. Vivancos , P. Diz , Á. Martín , M. Carasol , A. Frank

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引用次数: 0

Abstract

Objective

This article reviews the scientific evidence on the relationship between periodontitis and neurological disease, and particularly cerebrovascular disease and dementia. We also issue a series of recommendations regarding the prevention and management of periodontitis and these neurological diseases at dental clinics and neurology units.

Development

In response to a series of questions proposed by the SEPA-SEN Working Group, a literature search was performed, with no restrictions on study design, to identify the most relevant articles on the association between periodontitis and cerebrovascular disease and dementia from the perspectives of epidemiology, treatment, and the biological mechanisms involved in these associations.

Conclusions

Periodontitis increases the risk of ischaemic stroke and Alzheimer dementia. Recurrent bacterial infections and increased low-grade systemic inflammation seem to be possible biological mechanisms underlying this association. Limited evidence suggests that various oral health interventions can reduce the future risk of cerebrovascular disease and dementia.

查看原文本刊更多论文

牙周炎、脑血管疾病和痴呆症之间的关联。西班牙牙周病学协会和西班牙神经病学协会工作组的科学报告。

本文回顾了牙周炎与神经系统疾病，尤其是脑血管疾病和痴呆症之间关系的科学证据。针对 SEPA-SEN 工作组提出的一系列问题，我们进行了一次文献检索，对研究设计没有限制，目的是从流行病学、治疗以及这些关联所涉及的生物机制等角度，找出牙周炎与脑血管疾病和痴呆症之间关联的最相关文章。结论牙周炎会增加缺血性中风和阿尔茨海默氏症痴呆症的风险。反复细菌感染和低度全身炎症的增加似乎是这种关联的可能生物机制。有限的证据表明，各种口腔健康干预措施可以降低未来罹患脑血管疾病和痴呆症的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurologia 医学-临床神经学

CiteScore

5.90

自引率

2.60%

发文量

135

审稿时长

48 days

期刊介绍： Neurología es la revista oficial de la Sociedad Española de Neurología y publica, desde 1986 contribuciones científicas en el campo de la neurología clínica y experimental. Los contenidos de Neurología abarcan desde la neuroepidemiología, la clínica neurológica, la gestión y asistencia neurológica y la terapéutica, a la investigación básica en neurociencias aplicada a la neurología. Las áreas temáticas de la revistas incluyen la neurologia infantil, la neuropsicología, la neurorehabilitación y la neurogeriatría. Los artículos publicados en Neurología siguen un proceso de revisión por doble ciego a fin de que los trabajos sean seleccionados atendiendo a su calidad, originalidad e interés y así estén sometidos a un proceso de mejora. El formato de artículos incluye Editoriales, Originales, Revisiones y Cartas al Editor, Neurología es el vehículo de información científica de reconocida calidad en profesionales interesados en la neurología que utilizan el español, como demuestra su inclusión en los más prestigiosos y selectivos índices bibliográficos del mundo.