Insulina i upadek wieży z kości słoniowej. Rzecz o zmieniających się uwarunkowaniach innowacyjności

M. Kopczyński
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Abstract

Insulin and a fall of the ivory tower. On the changing determinants of innovation The centennial of the discovery of insulin and the fortieth anniversary of the introduction of human insulin into the American market provide a good opportunity to reflect on the circumstances surrounding innovation in high technology branches of industry. The subject of that reflection is the possibility of applying the model of technical, organisational and institutional co-evolution, formulated by Johan Peter Murmann in relation to the artificial dyes industry in nineteenth-century Germany, United Kingdom and United States, to the history of the pharmaceutical industry. An analysis of the evolution of relations between scientists and physicians on the one hand and the pharmaceutical industry on the other leads to the conclusion that the Murmann model must be supplemented with reflection on changes in the role of medical codes of ethics and on the understanding of the social role of science. The achievement of the current status quo in the cooperation between the medical profession and the industry has been possible thanks to the liberalisation of the principles of ethical codes, which have been transformed from a set of strict standards into just a set of guidelines to help physicians in their everyday practice. On the other hand, the industry has gradually adapted its marketing strategies to the requirements of physicians by divulging the composition of medicines, abandoning direct advertising to patients and introducing a new strategy known as scientific marketing. As far as scientists are concerned, the consent to the commercialisation of research results was the consequence of a change in the understanding of the social role of science. In the twentieth century science became one of the many professions pursued to earn a living and scientists no longer came to regard themselves as a special group selflessly explaining the rules of the natural world. It is unfair to blame biotechnology for this shift, as the processes of “disenchantment” of science were well under way before biotechnology was born in the mid-1970s.
胰岛素与象牙塔的倒塌。不断变化的创新条件
胰岛素和象牙塔的坍塌。胰岛素发现一百周年和人胰岛素进入美国市场四十周年为我们提供了一个很好的机会来思考高科技行业创新的相关情况。这一思考的主题是将约翰-彼得-穆尔曼(Johan Peter Murmann)针对十九世纪德国、英国和美国的人工染料工业提出的技术、组织和制度共同演变模式应用于制药业历史的可能性。通过对科学家和医生与制药业之间关系演变的分析,我们得出结论:必须对穆尔曼模式进行补充,对医学伦理准则作用的变化以及对科学的社会作用的理解进行反思。医学界与制药业之间的合作之所以能达到目前的现状,要归功于伦理规范原则的自由化,伦理规范已从一套严格的标准转变为一套帮助医生进行日常实践的指导方针。另一方面,医药行业也逐渐根据医生的要求调整了营销策略,公开了药品成分,放弃了直接向患者做广告,并引入了一种被称为科学营销的新策略。就科学家而言,同意研究成果商业化是对科学的社会作用的认识发生变化的结果。20 世纪,科学成为谋生的众多职业之一,科学家们不再把自己视为无私地解释自然界规则的特殊群体。将这一转变归咎于生物技术是不公平的,因为在 20 世纪 70 年代中期生物技术诞生之前,科学的 "迷失 "过程就已经开始了。
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