Second look, in primary site recurrence or second primary for T1 and T2 glottic cancer treated by CO2 laser

K. Luna-Ortiz, V. Villavicencio-Valencia, Zelik Luna-Peteuil, Diana Villavicencio-Valencia, D. García-Ortega, Philippe Pasche
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Abstract

Background: Aim was to analyze the impact of second-look surgery in the surveillance of T1 and T2 glottic cancer treated with CO2 laser. Methods: Retrospective review of 98 patients treated between February 2005 and December 2022. Results: Among 98 patients with early glottic cancer (T1/T2), 56 (57%) with suspected recurrence underwent a second-look surgery. Of all patients, 38 (38.77%) recurred 6 months after initial resection, 17 of which (45%) had a lesion in a different site from the primary. Of these 38 patients, 22 (58%) underwent laser surgery once, 12 (32%) underwent laser surgery twice, and 4 (10%) underwent laser surgery on three occasions during follow-up. The 5-year disease-free survival, 5-year survival, and larynx preservation rates were, respectively, 54%, 82%, and 90.8%.  Conclusions: Transoral resection is currently the first treatment option for early-stage glottic carcinoma because diagnosis and prompt treatment can be provided on an outpatient basis at the same time.
通过二氧化碳激光治疗 T1 和 T2 声门癌的原发部位复发或第二原发时的第二次观察
背景目的:分析二诊手术对CO2激光治疗T1和T2声门癌监测的影响:方法:回顾性分析2005年2月至2022年12月期间接受治疗的98例患者:在98例早期声门癌(T1/T2)患者中,有56例(57%)疑似复发,接受了二次复查手术。在所有患者中,38例(38.77%)在初次切除术后6个月复发,其中17例(45%)的病变部位与原发部位不同。在这38名患者中,22人(58%)接受过一次激光手术,12人(32%)接受过两次激光手术,4人(10%)在随访期间接受过三次激光手术。5年无病生存率、5年生存率和喉部保留率分别为54%、82%和90.8%。结论:经口切除术是目前治疗喉癌的首选方法:经口切除术是目前早期声门癌的首选治疗方法,因为在门诊就能同时进行诊断和及时治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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