Effectiveness of neoadjuvant chemoradiotherapy in the treatment of rectal cancer: A comprehensive study

Abstract

This study addresses the global health challenge of rectal cancer, aiming to assess the effectiveness of neoadjuvant chemoradiotherapy and its implications for treatment outcomes in 100 retrospectively analyzed patients. The cohort underwent neoadjuvant chemoradiotherapy followed by sphincter-sparing surgery, with recorded parameters including demographics, tumor stage, treatment protocol, and surgical outcomes. Results indicated tumor reduction in 80% of patients, with a 15% complication rate for sphincter-sparing surgery. Pathological examination underscored neoadjuvant treatment’s impact on tumor regression and reduced lymph node metastasis. In conclusion, the study emphasizes the demonstrated efficacy of neoadjuvant chemoradiotherapy in rectal cancer treatment, advocating for a comprehensive approach to managing this condition.